DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4676 and ZDHHC8

DIOPT Version :9

Sequence 1:NP_610853.1 Gene:CG4676 / 36465 FlyBaseID:FBgn0033815 Length:284 Species:Drosophila melanogaster
Sequence 2:NP_001171953.1 Gene:ZDHHC8 / 29801 HGNCID:18474 Length:778 Species:Homo sapiens


Alignment Length:308 Identity:71/308 - (23%)
Similarity:117/308 - (37%) Gaps:91/308 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 RVKPRSISDFACFLLVAVFVPVTYIFHVTIVMPELFAIGGIWYTLLWLA-----------SLFLI 62
            |:||            |.::||.....:.:....||.:    :|..||.           .:..:
Human     8 RLKP------------AKYIPVATAAALLVGSSTLFFV----FTCPWLTRAVSPAVPVYNGIIFL 56

  Fly    63 FNITSNMLACMLVDTSI---------RKELLKPPL----DAAQL---ARWHSCQDCQTLVPPRSW 111
            | :.:|......:|..:         :::..:.||    |...:   .:|  |..|....|||..
Human    57 F-VLANFSMATFMDPGVFPRADEDEDKEDDFRAPLYKNVDVRGIQVRMKW--CATCHFYRPPRCS 118

  Fly   112 HCEVCNVCVLKRDHHCRFTCCCIGHHNYRYFFYYLVYM---IIGSLAAAIMESIYLWHLHLDIYW 173
            ||.||:.||...||||.:...|||..||||||.:|:.:   ::|.:|..:   :|:.: |.:...
Human   119 HCSVCDNCVEDFDHHCPWVNNCIGRRNYRYFFLFLLSLSAHMVGVVAFGL---VYVLN-HAEGLG 179

  Fly   174 RWSTLFTIFAPVVSLMLSPSWESFYLVIYDLTLLGFAISSLLLVFHWSIFKSGSVTRER------ 232
            ...|..|:....|:.:       |::.:..||           .||..:...|..|.|:      
Human   180 AAHTTITMAVMCVAGL-------FFIPVIGLT-----------GFHVVLVTRGRTTNEQVTGKFR 226

  Fly   233 -GTRKYDRGLRGNLEMVLGKRMHLTWL-------------SPFLRSDL 266
             |...:.||..||:|.||...:...::             .||||.:|
Human   227 GGVNPFTRGCCGNVEHVLCSPLAPRYVVEPPRLPLAVSLKPPFLRPEL 274

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4676NP_610853.1 zf-DHHC 99..232 CDD:279823 39/135 (29%)
ZDHHC8NP_001171953.1 DHHC 99..224 CDD:366691 41/148 (28%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 293..352
PHA03247 <333..771 CDD:223021
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 509..540
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5273
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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