DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4676 and ZDHHC1

DIOPT Version :9

Sequence 1:NP_610853.1 Gene:CG4676 / 36465 FlyBaseID:FBgn0033815 Length:284 Species:Drosophila melanogaster
Sequence 2:NP_037436.1 Gene:ZDHHC1 / 29800 HGNCID:17916 Length:485 Species:Homo sapiens


Alignment Length:215 Identity:53/215 - (24%)
Similarity:86/215 - (40%) Gaps:52/215 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    55 WLASLFLI---FNITSNML---------ACM-------LV-----------DTSIRKELLKPPLD 89
            ||..||..   |.|...:|         |||       ||           |.::|.:....||.
Human    56 WLLYLFFAVIGFGILVPLLPHHWVPAGYACMGAIFAGHLVVHLTAVSIDPADANVRDKSYAGPLP 120

  Fly    90 AAQLARWHS-------CQDCQTLVPPRSWHCEVCNVCVLKRDHHCRFTCCCIGHHNYRYFFYYLV 147
            ....:: |:       |..|...|..||.||..||.||...||||::...|:|..|||.|.:.:.
Human   121 IFNRSQ-HAHVIEDLHCNLCNVDVSARSKHCSACNKCVCGFDHHCKWLNNCVGERNYRLFLHSVA 184

  Fly   148 YMIIGSLAAAIMESIYLW------------HLHLDIYWRWSTLFTIFAPVVSL-MLSPSWESFYL 199
            ..::|.| ..::.:.|::            :.|.::....:.::.:|.|...: ..:|:..:...
Human   185 SALLGVL-LLVLVATYVFVEFFVNPMRLRTNRHFEVLKNHTDVWFVFLPAAPVETQAPAILALAA 248

  Fly   200 VIYDLTLLGFAISSLLLVFH 219
            ::..|.||..|:...||.||
Human   249 LLILLGLLSTALLGHLLCFH 268

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4676NP_610853.1 zf-DHHC 99..232 CDD:279823 36/134 (27%)
ZDHHC1NP_037436.1 Mediates interaction with STING1. /evidence=ECO:0000269|PubMed:25299331 1..271 53/215 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..41
zf-DHHC 129..284 CDD:307600 36/141 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 324..358
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 462..485
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5273
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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