Protein Alignment CG4676 and ZDHHC1

DIOPT Version :10

• Sequence 1: NP_610853.1
• Gene: CG4676 / 36465
• FlyBaseID: FBgn0033815
• Length: 284
• Species: Drosophila melanogaster
• Sequence 2: NP_037436.1
• Gene: ZDHHC1 / 29800
• HGNCID: 17916
• Length: 485
• Species: Homo sapiens
• Alignment Length: 215
• Identity: 53/215 - (24%)
• Similarity: 86/215 - (40%)
• Gaps: 52/215 - (24%)

  Fly    55 WLASLFLI---FNITSNML---------ACM-------LV-----------DTSIRKELLKPPLD 89
            ||..||..   |.|...:|         |||       ||           |.::|.:....||.
Human    56 WLLYLFFAVIGFGILVPLLPHHWVPAGYACMGAIFAGHLVVHLTAVSIDPADANVRDKSYAGPLP 120

  Fly    90 AAQLARWHS-------CQDCQTLVPPRSWHCEVCNVCVLKRDHHCRFTCCCIGHHNYRYFFYYLV 147
            ....:: |:       |..|...|..||.||..||.||...||||::...|:|..|||.|.:.:.
Human   121 IFNRSQ-HAHVIEDLHCNLCNVDVSARSKHCSACNKCVCGFDHHCKWLNNCVGERNYRLFLHSVA 184

  Fly   148 YMIIGSLAAAIMESIYLW------------HLHLDIYWRWSTLFTIFAPVVSL-MLSPSWESFYL 199
            ..::|.| ..::.:.|::            :.|.::....:.::.:|.|...: ..:|:..:...
Human   185 SALLGVL-LLVLVATYVFVEFFVNPMRLRTNRHFEVLKNHTDVWFVFLPAAPVETQAPAILALAA 248

  Fly   200 VIYDLTLLGFAISSLLLVFH 219
            ::..|.||..|:...||.||
Human   249 LLILLGLLSTALLGHLLCFH 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4676	NP_610853.1	DHHC	99..232	CDD:396215	36/134 (27%)
ZDHHC1	NP_037436.1	Mediates interaction with STING1. /evidence=ECO:0000269|PubMed:25299331	1..271		53/215 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..41
		DHHC	129..284	CDD:396215	36/141 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	324..358
		DPBB_RlpA_EXP_N-like	<362..>400	CDD:455124
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	462..485