Protein Alignment CG4676 and ZDHHC22

DIOPT Version :9

• Sequence 1: NP_610853.1
• Gene: CG4676 / 36465
• FlyBaseID: FBgn0033815
• Length: 284
• Species: Drosophila melanogaster
• Sequence 2: NP_001351101.1
• Gene: ZDHHC22 / 283576
• HGNCID: 20106
• Length: 263
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 78/292 - (26%)
• Similarity: 116/292 - (39%)
• Gaps: 75/292 - (25%)

  Fly     1 MMILRSWDRVKPRSISDFACFLLVAVFVPVTYIFHVTIVMPELF---AIGGIWYTLLWLASLFLI 62
            |:.||..:.|.|      |.||.:::   ||::..:.:.:|.:.   |...::...|...:|||.
Human     1 MLALRLLNVVAP------AYFLCISL---VTFVLQLFLFLPSMREDPAAARLFSPALLHGALFLF 56

  Fly    63 FNITSNMLA--CMLVDTSIRKELLKPPLDAAQLARWHSCQDC---QTLVPPRSWH-CEVCNVCVL 121
              :::|.|.  .:::..|        |.|..      :||..   :|..|..|.| |.||....|
Human    57 --LSANALGNYVLVIQNS--------PDDLG------ACQGASARKTPCPSPSTHFCRVCARVTL 105

  Fly   122 KRDHHCRFTCCCIGHHNYRYFFYYLVYMIIGSLAAAIMESIYLWHLHLDIYWRWSTLFTI-FA-P 184
            :.||||.||..|||..|.|.|..:.:|..:..|.:.:....|:           |.:.:| || |
Human   106 RHDHHCFFTGNCIGSRNMRNFVLFCLYTSLACLYSMVAGVAYI-----------SAVLSISFAHP 159

  Fly   185 VVSLMLSP-SWESFY------------LVIY-----DLTLLGFAISSLLLVFHWSI---FKSGSV 228
            :..|.|.| |...|:            |::|     .|...||....|||:.....   .:.|..
Human   160 LAFLTLLPTSISQFFSGAVLGSEMFVILMLYLWFAIGLACAGFCCHQLLLILRGQTRHQVRKGVA 224

  Fly   229 TRERGTRKYDRGLRGNLEMVLGKRMHLTWLSP 260
            .|.|..||       ||:.|.|||..|..|.|
Human   225 VRARPWRK-------NLQEVFGKRWLLGLLVP 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4676	NP_610853.1	zf-DHHC	99..232	CDD:279823	45/159 (28%)
ZDHHC22	NP_001351101.1	DHHC	92..218	CDD:366691	39/136 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3153
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22883
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.860