DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4676 and Zdhhc13

DIOPT Version :9

Sequence 1:	NP_610853.1	Gene:	CG4676 / 36465	FlyBaseID:	FBgn0033815	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_082307.1	Gene:	Zdhhc13 / 243983	MGIID:	1919227	Length:	622	Species:	Mus musculus

Alignment Length:	274	Identity:	67/274 - (24%)
Similarity:	109/274 - (39%)	Gaps:	62/274 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 ACFLLVAVFVPVTYIFHVTIVMPELFAIGGI-WYTLLWLASLF-------LIFNITSNMLACM-- 73
            |.|.|.::|......:...:.:|.:|.:..| |..:.|....|       |.|....:::|.:
Mouse   326 ALFFLTSLFPRFLVGYKNLVYLPTVFLLSSIFWIFMTWFILFFPDTAGSPLYFAFIFSIMAFLYF 390

  Fly    74 -----LVD---TSIRKELLKPPLDAAQLARWHS------CQDCQTLVPPRSWHCEVCNVCVLKRD 124
                 ..|   |...:|..|  ::...||...|      |..|....|.||.||.|||.||.:.|
Mouse   391 FYKTWATDPGFTKASEEERK--VNIVTLAETGSLDFRTFCTSCLIRKPLRSLHCHVCNSCVARFD 453

  Fly   125 HHCRFTCCCIGHHNYRYFFYYLV-------YMIIGSLAAAIMESIYLWHLHLDIYWRWSTLFTIF 182
            .||.:|..|||..|:.::.::|:       ::|.||.       :| |..|....::...|:|..
Mouse   454 QHCFWTGRCIGFGNHHHYIFFLLSLSMVCDWIIYGSF-------VY-WSNHCATTFKEDGLWTYL 510

  Fly   183 APVVS--------LMLSP---SWESFYLV--IYDLTLLGFAISSLLLVFHWSIFK-SGSVTRERG 233
            ..:|:        .||:.   ||.:|.|:  ::.:..||......:     |:.| |..:.:...
Mouse   511 NQIVACSPWVLYIFMLAAFHFSWSTFLLINQLFQIAFLGLTSHERI-----SLLKQSRHMKQTLS 570

  Fly   234 TRK--YDRGLRGNL 245
            .||  |:.|...||
Mouse   571 LRKTPYNLGFTQNL 584

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4676	NP_610853.1	zf-DHHC	99..232	CDD:279823	41/153 (27%)
Zdhhc13	NP_082307.1	ANK 1. /evidence=ECO:0000250\|UniProtKB:Q8IUH5	43..78
		ANK	79..192	CDD:238125
		ANK repeat	81..112	CDD:293786
		ANK 2. /evidence=ECO:0000255	81..110
		Ank_2	86..179	CDD:289560
		ANK repeat	114..146	CDD:293786
		ANK 3. /evidence=ECO:0000255	115..144
		ANK repeat	148..179	CDD:293786
		ANK 4. /evidence=ECO:0000255	148..177
		ANK	176..>269	CDD:238125
		ANK repeat	181..247	CDD:293786
		ANK 5. /evidence=ECO:0000255	181..211
		Ank_5	202..257	CDD:290568
		ANK 6. /evidence=ECO:0000255	216..245
		ANK 7. /evidence=ECO:0000255	249..277
		zf-DHHC	423..556	CDD:279823	38/140 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900