DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4676 and dhhc-13

DIOPT Version :9

Sequence 1:	NP_610853.1	Gene:	CG4676 / 36465	FlyBaseID:	FBgn0033815	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_500889.2	Gene:	dhhc-13 / 186797	WormBaseID:	WBGene00019257	Length:	593	Species:	Caenorhabditis elegans

Alignment Length:	233	Identity:	58/233 - (24%)
Similarity:	100/233 - (42%)	Gaps:	55/233 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 VKPRSISDFACFLLVAVFVPVTYIFHVTIVMPEL--FAIGGI--WYTLLWLASLFLIFNITSNML 70
            |:.|.:..|.|       :||||||.:.|....|  |...|:  |..|:::.|:::|    |...
Worm   320 VQRRQMDQFGC-------LPVTYIFWMGIAEFALLIFNSNGLVHWSVLIFVCSIWVI----SASF 373

  Fly    71 ACMLV---------DTSIRKELLKPPLDAAQLARWHSCQDCQTLVPPRSWHCEVCNVCVLKRDHH 126
            ..:|:         .|:..|:.:| .|:..|:.|:  |..|.......|.||..|:.||...|||
Worm   374 YWILILTNPGVLPRSTTPFKDFIK-DLEEKQIDRY--CFTCWIPKTSSSHHCSQCDKCVDGFDHH 435

  Fly   127 CRFTCCCIGHHNYRYFFYYLVYMIIGSLAAAIMESIYLWHLHLDIYWRWSTLFTIFAPVVSLMLS 191
            |.:...|:...|.|.|.::.:             :|:::|    :::....|:.|.|       |
Worm   436 CPWIHKCVYRKNLRAFVFFCL-------------TIFMFH----VFYVLLLLYMIGA-------S 476

  Fly   192 PSWESFYLVIYDLTLLGFAISSLLLVFHWSIFKSGSVT 229
            .:...|...:.|..|:  .||.:|.:.|  :|.:|::|
Worm   477 MNASGFEQTLNDHGLM--VISLILAIPH--VFGAGAIT 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4676	NP_610853.1	zf-DHHC	99..232	CDD:279823	32/131 (24%)
dhhc-13	NP_500889.2	ANK	42..155	CDD:238125
		Ank_2	42..132	CDD:289560
		ANK repeat	67..98	CDD:293786
		ANK repeat	101..132	CDD:293786
		Ank_5	121..176	CDD:290568
		ANK	130..>240	CDD:238125
		Ank_5	198..243	CDD:290568
		ANK repeat	206..234	CDD:293786
		zf-DHHC	405..530	CDD:279823	33/136 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810