DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4676 and dhhc-14

DIOPT Version :9

Sequence 1:	NP_610853.1	Gene:	CG4676 / 36465	FlyBaseID:	FBgn0033815	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_001024514.2	Gene:	dhhc-14 / 181109	WormBaseID:	WBGene00044071	Length:	565	Species:	Caenorhabditis elegans

Alignment Length:	182	Identity:	42/182 - (23%)
Similarity:	67/182 - (36%)	Gaps:	37/182 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 PRSISDFACFL-LVAVFVPVTYIFH----------VTIVMPELFAIG----GIWYTLLWLASLFL 61
            |..|:.|:..: .:.:.|.:.:.:|          |||....|..:.    ..||...|...||:
Worm   291 PLIIATFSTLISCIFLMVLIRFDYHDPTYKLLPYGVTIAEAILMVLSWSAYAHWYVPWWAQMLFV 355

  Fly    62 IFNITSNMLACMLVDTSIRKELLKPP------------LDAAQLARWHS---CQDCQTLVPPRSW 111
            :     ::||  |..|..|...|.|.            ::.|:....|.   |..|.......:.
Worm   356 L-----SVLA--LAFTLFRIGTLDPGVVRAAKNCHQLFVNEAEAGIQHQQKYCFTCFIRKMDHTK 413

  Fly   112 HCEVCNVCVLKRDHHCRFTCCCIGHHNYRYFFYYLVYMIIGSLAAAIMESIY 163
            ||.||..||...||||.:...|:...|.|.|..:::.:.:.|....:..|.|
Worm   414 HCAVCGFCVNNFDHHCPWLNSCVTRRNMREFIMFVISVSVSSAIYCMATSHY 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4676	NP_610853.1	zf-DHHC	99..232	CDD:279823	19/65 (29%)
dhhc-14	NP_001024514.2	ANK	19..143	CDD:238125
		Ank_2	30..120	CDD:289560
		ANK repeat	55..87	CDD:293786
		ANK repeat	89..120	CDD:293786
		Ank_2	94..222	CDD:289560
		ANK	117..244	CDD:238125
		ANK repeat	190..222	CDD:293786
		PulO	<261..>367	CDD:224900	18/82 (22%)
		zf-DHHC	394..521	CDD:279823	20/72 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910