DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG4676 and ZDHHC19

DIOPT Version :9

Sequence 1:NP_610853.1 Gene:CG4676 / 36465 FlyBaseID:FBgn0033815 Length:284 Species:Drosophila melanogaster
Sequence 2:NP_001034706.1 Gene:ZDHHC19 / 131540 HGNCID:20713 Length:309 Species:Homo sapiens


Alignment Length:263 Identity:62/263 - (23%)
Similarity:102/263 - (38%) Gaps:76/263 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    40 MPELFA---------IGGIWYTL--LWLA------------SLFLI--FNITSNMLACMLVDTSI 79
            :|.|||         ..|:::..  .|||            |||::  |::.|...:    |..|
Human    26 LPSLFAAFNVVLLVFFSGLFFAFPCRWLAQNGEWAFPVITGSLFVLTFFSLVSLNFS----DPGI 86

  Fly    80 --RKELLKPPL--------DAAQLARWHSCQDCQTLVPPRSWHCEVCNVCVLKRDHHCRFTCCCI 134
              :....:.||        ..|...:|  |..|....|||::||..||:||...||||::...||
Human    87 LHQGSAEQGPLTVHVVWVNHGAFRLQW--CPKCCFHRPPRTYHCPWCNICVEDFDHHCKWVNNCI 149

  Fly   135 GHHNYRYFFYYLVYMIIGSLAAAIMESIYLWHLHLDIYWRWSTLFTIFAPVVSLMLSPSWESFYL 199
            ||.|:|:|...::.:.:.|.|..:...|:|                    |.:..|..|.:....
Human   150 GHRNFRFFMLLVLSLCLYSGAMLVTCLIFL--------------------VRTTHLPFSTDKAIA 194

  Fly   200 VIYDLTLLGFAI--SSLLLVFHWSIFKS-----GSVTRERGTRKYDRGLRGNLEMVLGKRMHLTW 257
            ::..::..|..:  |.|||:...|:..:     |.....:|...:|:|...|        .:||.
Human   195 IVVAVSAAGLLVPLSLLLLIQALSVSSADRTYKGKCRHLQGYNPFDQGCASN--------WYLTI 251

  Fly   258 LSP 260
            .:|
Human   252 CAP 254

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4676NP_610853.1 zf-DHHC 99..232 CDD:279823 36/139 (26%)
ZDHHC19NP_001034706.1 DHHC 109..>181 CDD:366691 27/93 (29%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 280..309
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5273
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.