DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Qsox1 and QSOX1

DIOPT Version :9

Sequence 1:	NP_001286383.1	Gene:	Qsox1 / 36464	FlyBaseID:	FBgn0033814	Length:	637	Species:	Drosophila melanogaster
Sequence 2:	NP_172955.1	Gene:	QSOX1 / 838067	AraportID:	AT1G15020	Length:	528	Species:	Arabidopsis thaliana

Alignment Length:	618	Identity:	143/618 - (23%)
Similarity:	238/618 - (38%)	Gaps:	196/618 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSATHLVILAVALLVDIASAGVPLPRYEALLKQQSPPSDPTLGLYDDGDKVIRLSVDNFNATVLD 65
            ||..||.:|...|.::.|::..|..|  ::|:      |....:.|..|..|.|:..||::...|
plant     1 MSLIHLFLLLGLLSLEAAASFSPGSR--SILR------DIGSNVADQKDNAIELNATNFDSVFQD 57

  Fly    66 Q-NRGALVEFYNTYCGHCRRFAPTYKSV------AEHLLPWSEVLIVAAIDCAAEENNGICRNYE 123
            . .:.|::||:..:|..||.:.|.|:.|      |:.:.|  .|:::..:|||.:.|..:|..:.
plant    58 SPAKYAVLEFFAHWCPACRNYKPHYEKVARLFNGADAVYP--GVVLMTRVDCAIKMNVKLCDKFS 120

  Fly   124 VMGYPTL------RYLGPGFQPGPQHYGQSLHTQDKNEIREILAGMVAAENLTSSHNNSYWPNFH 182
            :..||.|      |::|..:  ||:        |:||||
plant   121 INHYPMLFWAPPKRFVGGSW--GPK--------QEKNEI-------------------------- 149

  Fly   183 YLTENDSASSLFEGLSSATEYVAVVHEPENTTLGVEVALFMTQWPAVRVRRVIDPAVAAKFKIDP 247
                                  :||:|.....|       :..|        |:..:.:.:.:|.
plant   150 ----------------------SVVNEWRTADL-------LLNW--------INKQIGSSYGLDD 177

  Fly   248 TNLPLSLVDRKGEITAYAPESTNGESYAKKLWDVLGKKNITPRPVKVHQPSATPASKIKGQNELI 312
                                        :||.::|                    |.|..|.::.
plant   178 ----------------------------QKLGNLL--------------------SNISDQEQIS 194

  Fly   313 DEVHRNKHFVYQADLEQAIRTVLHNEVSKVGEISGEKLLALQRFLAVLQRYNPLGANGHQLVSKL 377
            ..:     |..:...|:|...:|.::..|..|.|...:    |||.:|..::|    ..:..:..
plant   195 QAI-----FDIEEATEEAFDIILAHKAIKSSETSASFI----RFLQLLVAHHP----SRRCRTGS 246

  Fly   378 KDYVVQFNDQRLTGS-QFEEELKRLEAHLSPVYSSNHFVG----------CVGSSPRLRGFSCSL 431
            .:.:|.|:|...:|. .:::|....::     ..:.|..|          |.||....|||||.|
plant   247 AEILVNFDDICPSGECSYDQESGAKDS-----LRNFHICGKDVPRGYYRFCRGSKNETRGFSCGL 306

  Fly   432 WTLFHFMTVQAANNEETQDPLEVLQAMHGYIKNFFGCTECSEHFQAMASRRKIWSVPNKE--EAV 494
            |.|.|.::|:..:.|..    ....|:..:|.|||.|.:|..||..|....|   .|.|:  :..
plant   307 WVLMHSLSVRIEDGESQ----FAFTAICDFINNFFMCDDCRRHFHDMCLSVK---TPFKKARDIA 364

  Fly   495 LWLWAAHNEVNQRLAGD----ATEDPEFPKKQFPAPESCNECYRTPVSKSENLEIEWNKDAVLGF 555
            ||||:.||:||:||..|    .|.||:|||..:|..:.|..||.:...|:    |:|:.|.|..|
plant   365 LWLWSTHNKVNERLKKDEDSLGTGDPKFPKMIWPPKQLCPSCYLSSTEKN----IDWDHDQVYKF 425

  Fly   556 LKNIHNPQFVSRY-----GVQREELLHPTADKM 583
            ||..:..:.||.|     .|.:||:: ..|::|
plant   426 LKKYYGQKLVSVYKKNGESVSKEEVI-AAAEEM 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Qsox1	NP_001286383.1	PDI_a_QSOX	49..162	CDD:239290	35/125 (28%)
Qsox1	NP_001286383.1	Evr1_Alr	430..521	CDD:282612	35/96 (36%)
QSOX1	NP_172955.1	PDI_a_QSOX	41..161	CDD:239290	39/186 (21%)
QSOX1	NP_172955.1	Evr1_Alr	305..394	CDD:282612	34/95 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	65	1.000	Domainoid score	I3612
eggNOG	1	0.900	-	-		E1_KOG1731
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	163	1.000	Inparanoid score	I1610
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D498515at2759
OrthoFinder	1	1.000	-	-		FOG0001506
OrthoInspector	1	1.000	-	-		mtm1146
orthoMCL	1	0.900	-	-		OOG6_102428
Panther	1	1.100	-	-	O	PTHR22897
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1232
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.870