DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Qsox1 and QSOX2

DIOPT Version :9

Sequence 1:	NP_001286383.1	Gene:	Qsox1 / 36464	FlyBaseID:	FBgn0033814	Length:	637	Species:	Drosophila melanogaster
Sequence 2:	NP_565258.1	Gene:	QSOX2 / 814654	AraportID:	AT2G01270	Length:	495	Species:	Arabidopsis thaliana

Alignment Length:	648	Identity:	154/648 - (23%)
Similarity:	246/648 - (37%)	Gaps:	196/648 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSATHLVILAVALLVDIASAGVPLPRYEALLKQQSPPSDPTLGLYDDGDKVIRLSVDNFNATVLD 65
            ||..||::.|.  ||..||:..|..|  .:|::.|          |..||.:.|:..||::.:.|
plant     1 MSLVHLLLFAG--LVIAASSSSPGSR--LILREIS----------DQKDKAVELNTTNFDSVLKD 51

  Fly    66 -QNRGALVEFYNTYCGHCRRFAPTYKSVA------EHLLPWSEVLIVAAIDCAAEENNGICRNYE 123
             ..:.|:|||:..:|..||.:.|.|:.||      :.:.|  .::::..:|||.:.|..:|..:.
plant    52 TPAKYAVVEFFAHWCPACRNYKPHYEKVARLFNGPDAIHP--GIVLMTRVDCAMKTNTKLCDKFS 114

  Fly   124 VMGYPTLRYLGPGFQPGPQHY--GQSLHTQDKNEIREILAGMVAAENLTSSHNNSYWPNFHYLTE 186
            |..||.| :.||     |..:  |.....:||:||..|..|. .||.|.:..|.....::..
plant   115 VSHYPML-FWGP-----PTKFVSGSWEPKKDKSEILVIDDGR-TAERLLNWINKQIGSSYGL--- 169

  Fly   187 NDSASSLFEGLSSATEYVAVVHEPENTTLGVEVALFMTQWPAVRVRRVIDPAVAAKFKIDPTNLP 251
            :|........||:.|:|                             ..|..||
plant   170 DDQKFKNEHALSNLTDY-----------------------------NQISQAV------------ 193

  Fly   252 LSLVDRKGEITAYAPESTNGESYAKKLWDVLGKKNITPRPVKVHQPSATPASKIKGQNELIDEVH 316
                        |..|....|::     |::    :..:.:|..:.||:
plant   194 ------------YDVEEATAEAF-----DII----LAHKAIKSSETSAS---------------- 221

  Fly   317 RNKHFVYQADLEQAIRTVLHNEVSKVGEISGEKLLALQRFLAVLQRYNPLGANGHQLVSKLK--- 378
                |:                                ||:.:|.        .|.|..:.:
plant   222 ----FI--------------------------------RFIQLLA--------AHHLSRRCRKGA 242

  Fly   379 -DYVVQFNDQRLTGS-QFEEELKRLEAHLSPVYSSN----HFVGCVGSSPRLRGFSCSLWTLFHF 437
             :.:|.::|...:|: .:|:..........|:...:    :::.|.||....|||||.||.|.|.
plant   243 AEILVNYDDLCPSGNCSYEKSGGNDTLGNFPICGKDVPRGYYMFCRGSKNDTRGFSCGLWVLMHS 307

  Fly   438 MTVQAANNEETQDPLEVLQAMHGYIKNFFGCTECSEHFQAMASRRKIWSVPNKE--EAVLWLWAA 500
            ::|:..:.|..    .....:..::.|||.|.||..||..|....|   .|.|:  :.|||:|:.
plant   308 LSVRIEDGESH----FAFTTICDFVNNFFMCDECRLHFNDMCLSVK---TPFKKARDFVLWVWST 365

  Fly   501 HNEVNQRLAGD----ATEDPEFPKKQFPAPESCNECYRTPVSKSENLEIEWNKDAVLGFLKNIHN 561
            ||:||:||..|    .|.||:|||..:|..|.|..||.:...||    |||:.:.|..||||.:.
plant   366 HNKVNERLLKDEASLGTGDPKFPKIIWPPKELCPLCYLSSNQKS----IEWDHEHVYKFLKNYYG 426

  Fly   562 PQFVSRYGVQREELLHPTADKMRQKRQISSVFTDMDMRMGMLLY----AFCIVMMVLAFKLFA 620
            |:.||.|   :|:.:      .|.|.:..|...|:.:....|:.    |..|.:...||...|
plant   427 PKLVSLY---KEKSV------SRSKEETVSATEDLTVATNALVVPIGAALAIAIASCAFGALA 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Qsox1	NP_001286383.1	PDI_a_QSOX	49..162	CDD:239290	36/121 (30%)
Qsox1	NP_001286383.1	Evr1_Alr	430..521	CDD:282612	34/96 (35%)
QSOX2	NP_565258.1	Thioredoxin_like	35..155	CDD:294274	39/128 (30%)
QSOX2	NP_565258.1	Evr1_Alr	300..390	CDD:282612	34/96 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	65	1.000	Domainoid score	I3612
eggNOG	1	0.900	-	-		E1_KOG1731
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	163	1.000	Inparanoid score	I1610
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D498515at2759
OrthoFinder	1	1.000	-	-		FOG0001506
OrthoInspector	1	1.000	-	-		mtm1146
orthoMCL	1	0.900	-	-		OOG6_102428
Panther	1	1.100	-	-	LDO	PTHR22897
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1232
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.870