Protein Alignment Qsox1 and QSOX1

DIOPT Version :10

• Sequence 1: NP_610852.1
• Gene: Qsox1 / 36464
• FlyBaseID: FBgn0033814
• Length: 637
• Species: Drosophila melanogaster
• Sequence 2: NP_002817.2
• Gene: QSOX1 / 5768
• HGNCID: 9756
• Length: 747
• Species: Homo sapiens
• Alignment Length: 599
• Identity: 195/599 - (32%)
• Similarity: 287/599 - (47%)
• Gaps: 95/599 - (15%)

  Fly    40 PTLGLYDDGDKVIRLSVDNFNATVLDQNRGALVEFYNTYCGHCRRFAPTYKSVAEHLLPWSEVLI 104
            |...||...|.:..|..|.....||.......|||:.::||||..||||:|::||.:..|...|.
Human    31 PRSALYSPSDPLTLLQADTVRGAVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALY 95

  Fly   105 VAAIDCAAEENNGICRNYEVMGYPTLRYLGPGFQPGPQHYGQSLHTQDKNEIREILAGMVAAENL 169
            :||:|||.|.|:.:||::.:.|:||:|:. ..|..........:...|...:||.|     .:.|
Human    96 LAALDCAEETNSAVCRDFNIPGFPTVRFF-KAFTKNGSGAVFPVAGADVQTLRERL-----IDAL 154

  Fly   170 TSSHNNSYWPNFHYLTENDSASSLFEGLSSAT--EYVAVVHEPENTTLGVEVALFMTQWPAVRVR 232
            .|.|:.  ||......|......: :|..:..  ||:|::.|...:.||.||||.::|...|.||
Human   155 ESHHDT--WPPACPPLEPAKLEEI-DGFFARNNEEYLALIFEKGGSYLGREVALDLSQHKGVAVR 216

  Fly   233 RVIDPAVAAKFKIDPTNLP-LSLVDRKGEITAYAPESTNGESYAKKLWDVLG------KKNITPR 290
            ||::.......|...|:.| ..|:.|.|.::.......:...|...|..:.|      :..:.|
Human   217 RVLNTEANVVRKFGVTDFPSCYLLFRNGSVSRVPVLMESRSFYTAYLQRLSGLTREAAQTTVAP- 280

  Fly   291 PVKVHQPSATPASKIKGQN-ELIDEVHRNKHFVYQADLEQAIRTVLHNEVSKVGEISGEKLLALQ 354
                     |.|:||.... :|.|   |:|  :|.||||.|:..:|..||.:...:.|::|:||:
Human   281 ---------TTANKIAPTVWKLAD---RSK--IYMADLESALHYILRIEVGRFPVLEGQRLVALK 331

  Fly   355 RFLAVLQRYNPLGANGHQLVSKLKDYVVQFNDQRLTGSQFEEELKRLEAHLSPVYS--------- 410
            :|:|||.:|.|    |..||......|             .|.|||.:.:..| ||
Human   332 KFVAVLAKYFP----GRPLVQNFLHSV-------------NEWLKRQKRNKIP-YSFFKTALDDR 378

  Fly   411 --------SNHFVGCVGSSPRLRGFSCSLWTLFHFMTVQAA-----NNEETQDPLEVLQAMHGYI 462
                    ..:::||.||.|..|||.||||.||||:|||||     :::|.....|||.|:.||:
Human   379 KEGAVLAKKVNWIGCQGSEPHFRGFPCSLWVLFHFLTVQAARQNVDHSQEAAKAKEVLPAIRGYV 443

  Fly   463 KNFFGCTECSEHFQAM--ASRRKIWSVPNKEEAVLWLWAAHNEVNQRLAGDATEDPEFPKKQFPA 525
            ..||||.:|:.||:.|  ||..::.| ||  .||||||::||.||.||||..:|||:|||.|:|.
Human   444 HYFFGCRDCASHFEQMAAASMHRVGS-PN--AAVLWLWSSHNRVNARLAGAPSEDPQFPKVQWPP 505

  Fly   526 PESCNECYRTPVSKSENLEIE-WNKDAVLGFLKNIHNPQFVSRYGVQREELLHPTADKMRQKRQI 589
            .|.|:.|:      :|.|::. |:.:|.|.|||...:|..:         :|...|.....:|.:
Human   506 RELCSACH------NERLDVPVWDVEATLNFLKAHFSPSNI---------ILDFPAAGSAARRDV 555

  Fly   590 SSVFTDMDMRMGML 603
            .:|....::.||.|
Human   556 QNVAAAPELAMGAL 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Qsox1	NP_610852.1	PDI_a_QSOX	49..162	CDD:239290	39/112 (35%)
		FAD_SOX	322..420	CDD:465728	32/114 (28%)
		Evr1_Alr	429..524	CDD:461423	54/101 (53%)
QSOX1	NP_002817.2	PDI_a_QSOX	40..152	CDD:239290	39/117 (33%)
		QSOX_Trx1	162..269	CDD:465653	27/107 (25%)
		FAD_SOX	295..396	CDD:465728	35/123 (28%)
		Evr1_Alr	405..504	CDD:461423	54/101 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	573..633