Protein Alignment Qsox1 and T10H10.2

DIOPT Version :9

• Sequence 1: NP_001286383.1
• Gene: Qsox1 / 36464
• FlyBaseID: FBgn0033814
• Length: 637
• Species: Drosophila melanogaster
• Sequence 2: NP_508419.1
• Gene: T10H10.2 / 180538
• WormBaseID: WBGene00020426
• Length: 574
• Species: Caenorhabditis elegans
• Alignment Length: 587
• Identity: 170/587 - (28%)
• Similarity: 273/587 - (46%)
• Gaps: 110/587 - (18%)

  Fly     6 LVILAVALLVDIASAGVPLPRYEALLKQQSPPSDPTLGLYDDGDKVIRLSVDNFNATVLDQNRGA 70
            |::|...:|.|||:.|           .....::||  ||...|.|::|....||.|:.....||
 Worm     4 LILLITPVLADIATYG-----------YHPKGANPT--LYSPEDSVLQLDEATFNDTIFGAQSGA 55

  Fly    71 ---LVEFYNTYCGHCRRFAPTYKSVAEHLLPWSEVLIVAAIDCAAEENNGICRNYEVMGYPTLRY 132
               |||||:.:|||||.||||||::|:.:..|..::.:|||:||...|..:||:..|..:|.::|
 Worm    56 AGYLVEFYSDWCGHCRAFAPTYKNLAKDVDGWQNIVKIAAINCADPVNEPVCRSNGVRFFPLIKY 120

  Fly   133 LGPGFQPGPQHYGQSLHTQDKNEIREILAGMVAAENLTSSHNNSY-------WPNFHYLTENDSA 190
            .       |:   .||::.:.::|:...........||.:..:.|       ||.|.:|.:..:.
 Worm   121 F-------PR---DSLNSTEGSQIKPYSTVSEMRGQLTKAVMDDYALNRYPEWPTFDFLKDVVTY 175

  Fly   191 SSLFEGLSSATEYVAVVHEPENTTL-GVEVALFMT-QWPAVRVRRVI-DPAVAAKFKIDPTNLPL 252
            ..|:...||:..::|::.|....:| |.::.|.:: ....:..||.: ...:|...||  |:.|.
 Worm   176 GELWNESSSSANHIAIIFETNQASLTGAQLLLDLSGNRDRLVARRCLKSHPLAEALKI--TDFPS 238

  Fly   253 SLVDRKGEITAYAPESTNGESYAKKLWDVLGKKNITPRPVKVHQPSATPASKIKGQNELID---- 313
            ..:.::||.......... ....:::...|||      |...|..:...:|:   :|:.||
 Worm   239 LAIFKRGERKPVLIAELR-RLLLREIDQFLGK------PTDNHLQTIHFSSR---KNKTIDCNKN 293

  Fly   314 -EVHRNKHFVYQADLEQAIRTVLHNEVSKVG-EISGEKLLALQRFLAVLQRYNPL----GANGHQ 372
             |:.:..:||.:.|:.:|:|..|..|.::.| .:....|.||..|.::|....|.    ||:.:.
 Worm   294 PELCKPNYFVSEVDMLKAMRYALFRESARTGAPLQAANLSALYEFTSLLADTFPTTTIEGASDNS 358

  Fly   373 LV-------------SKLKDYVVQFNDQRLTGSQFEEELKRLEAHLS-----------------P 407
            .|             |:|:|::.:               |.|||.:|                 |
 Worm   359 TVLHLDRSSRAVRVFSRLRDFIAE---------------KGLEAPISVEDWQKEFLAAEEEAGHP 408

  Fly   408 VYSSNHFVGCVGSSPRLRGFSCSLWTLFHFMTVQAANN--EETQD---PLEVLQAMHGYIKNFFG 467
            ...:.::..|.|||.:.||::|.|||.||.:||.|..|  .:|.|   ||..||::..::.:|||
 Worm   409 FPLNTNWEHCAGSSTQYRGYTCGLWTTFHALTVSAFKNWQNKTNDITLPLPPLQSIRDWVGSFFG 473

  Fly   468 CTECSEHFQAMASRR-KI-WSVPNKEEAVLWLWAAHNEVNQRLAGDATEDPEFPKKQFPAPESCN 530
            |..|.:||..|.:.. || .:|...|:..|:||.|||:||.||.|..||||:|||.||||...|.
 Worm   474 CNHCRDHFLKMTTDTFKIEANVRRPEDVYLYLWKAHNKVNARLHGRETEDPKFPKYQFPAKFLCV 538

  Fly   531 EC 532
            :|
 Worm   539 DC 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Qsox1	NP_001286383.1	PDI_a_QSOX	49..162	CDD:239290	41/115 (36%)
		Evr1_Alr	430..521	CDD:282612	44/97 (45%)
T10H10.2	NP_508419.1	PDI_a_QSOX	34..149	CDD:239290	42/124 (34%)
		Evr1_Alr	431..528	CDD:282612	43/96 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166868
Domainoid	1	1.000	91	1.000	Domainoid score	I4858
eggNOG	1	0.900	-	-		E1_KOG1731
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H37690
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4773
OMA	1	1.010	-	-		QHG48718
OrthoDB	1	1.010	-	-		D158783at33208
OrthoFinder	1	1.000	-	-		FOG0001506
OrthoInspector	1	1.000	-	-		mtm4857
orthoMCL	1	0.900	-	-		OOG6_102428
Panther	1	1.100	-	-	O	PTHR22897
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1232
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.670