DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Qsox1 and qsox2

DIOPT Version :9

Sequence 1:	NP_001286383.1	Gene:	Qsox1 / 36464	FlyBaseID:	FBgn0033814	Length:	637	Species:	Drosophila melanogaster
Sequence 2:	NP_001121505.1	Gene:	qsox2 / 100158617	XenbaseID:	XB-GENE-986398	Length:	657	Species:	Xenopus tropicalis

Alignment Length:	702	Identity:	188/702 - (26%)
Similarity:	315/702 - (44%)	Gaps:	149/702 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 VALLVDIASAGVPLPRYEALLKQQSPPSDPTLGLYDDGDKVIRLSVDNFNATVLDQNRGALVEFY 75
            :|:||...|.|.     ||              ||...|.:..|:.::....|.:.:...|:|||
Frog    12 LAVLVLFGSVGA-----EA--------------LYGPADPLSILNKESVTRAVFNSSSAWLLEFY 57

  Fly    76 NTYCGHCRRFAPTYKSVAEHLLPWSEVLIVAAIDCAAEENNGICRNYEVMGYPTLRYL------- 133
            :::||||..:|||::::|..:..|...:.:..:|||.|:|.|.|:::.|..|||.|:.
Frog    58 SSWCGHCINYAPTWRALARDVSDWDPAIKIGVLDCAEEDNYGTCKDFGVTLYPTFRFFKAFTTEF 122

  Fly   134 --GPGFQPGPQHYGQSLHTQDKNEIREILAGMVAAENLTSSHNNSYWPNFHYLTENDSASSLFEG 196
              |..::.|        :.::...:|:::...:......|.....  |....::.::.:|.|.:
Frog   123 TQGENYKAG--------NDREIQTVRQVIIDFLQTSPAQSKPQAC--PTLEPISSSEISSLLTQ- 176

  Fly   197 LSSATEYVAVVHEPENTTLGVEVALFMTQWPAVRVRRVI--DPAVAAKFKIDPTNLPLSLVDRKG 259
              ..:.|.|::.|.|.:.:|.||.|.:.::..:.|||.:  |.|:..|..|             |
Frog   177 --KQSHYTAIIFESEESYVGREVMLDLIRYSNMVVRRALPSDKAILEKLGI-------------G 226

  Fly   260 EITA---YAPESTNG------------ESYAKKLWDVLGKKNITPRPVKVHQPSATPASKIKGQN 309
            .:.:   ..|..::|            .|:.|.|.:|  :|.:         ||.|..|.:....
Frog   227 SVPSCYLIQPNGSHGLIKEVKCLRAQLSSHLKALPNV--RKRL---------PSDTAHSGLNKDA 280

  Fly   310 ELID----EVHRNKHFVYQADLEQAIRTVLHNEVSKVGEISGEKLLALQRFLAVLQRYNPLGANG 370
            :..|    |..|:|  :|.||||..:..||..|::....:.||||...:.|:.:|.:..|...:.
Frog   281 QQGDVAMKEFDRSK--LYMADLESGLHYVLRAELANHRTLEGEKLKTFKDFVTILYKLFPGRPHV 343

  Fly   371 HQLVSKLKDYVVQFNDQRLTGSQFEEELKRLEAHLSPVYSSNH--FVGCVGSSPRLRGFSCSLWT 433
            .:|:..|::::|.....::..... .:|......:|.::.:||  :|||.||...|||:.||||.
Frog   344 MKLLETLQEWLVSMPLDKIPYDAI-LDLVNNRMRISGIFLTNHTQWVGCRGSKSHLRGYPCSLWK 407

  Fly   434 LFHFMTVQA-------ANNEETQDPLEVLQAMHGYIKNFFGCTECSEHFQAMASRRKIWSVPNKE 491
            |||.:||||       ||.....||..|||.|..||:.||||.||::||:||| :..:.||...:
Frog   408 LFHSLTVQASVKPDALANTALGADPQAVLQTMRSYIREFFGCRECAKHFEAMA-KETMDSVRTPD 471

  Fly   492 EAVLWLWAAHNEVNQRLAGDATEDPEFPKKQFPAPESCNECYRTPVSKSENLEIEWNKDAVLGFL 556
            :||||||..||.||.||:|..:|||:|||.|:|..:.|:.|:......:::    ||::.||.||
Frog   472 QAVLWLWRKHNAVNNRLSGAPSEDPKFPKVQWPTSDLCSACHGQTGGGTQS----WNENEVLSFL 532

  Fly   557 KNIHNPQFVS-RYGVQREELLH-----------PT-----------------ADKMRQKRQISSV 592
            |..:..|.:| .:...|.|...           ||                 .||:...:...||
Frog   533 KRYYGKQEISLEFADHRTEQSEAADGHGNKEPLPTKKPEEGEDLKKNQGPQFLDKLIPNKPEKSV 597

  Fly   593 -----------------FTDMDMRMGMLLYAFCIVMMVLAFKLFAFKGYRKK 627
                             |:::||.:.::||....:.:::.:..|.|:..|.|
Frog   598 GSEAADTRQSVSFLGIGFSNIDMSLCVILYLTSSLFLMVMYFFFRFRSKRWK 649

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Qsox1	NP_001286383.1	PDI_a_QSOX	49..162	CDD:239290	31/121 (26%)
Qsox1	NP_001286383.1	Evr1_Alr	430..521	CDD:282612	51/97 (53%)
qsox2	NP_001121505.1	PDI_a_QSOX	31..145	CDD:239290	31/121 (26%)
		QSOX_Trx1	156..263	CDD:375557	24/124 (19%)
		FAD_SOX	291..394	CDD:375797	27/105 (26%)
		Evr1_Alr	403..503	CDD:368111	53/100 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	72	1.000	Domainoid score	I9185
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	258	1.000	Inparanoid score	I3055
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D158783at33208
OrthoFinder	1	1.000	-	-		FOG0001506
OrthoInspector	1	1.000	-	-		mtm9402
Panther	1	1.100	-	-	O	PTHR22897
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.160