DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pex13 and Pex13

DIOPT Version :9

Sequence 1:	NP_610850.1	Gene:	Pex13 / 36462	FlyBaseID:	FBgn0033812	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_076140.2	Gene:	Pex13 / 72129	MGIID:	1919379	Length:	405	Species:	Mus musculus

Alignment Length:	452	Identity:	134/452 - (29%)
Similarity:	205/452 - (45%)	Gaps:	89/452 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 ISDAPLLPPS-------SSIGVGVSSGGGYPPEAVLRTPYGNVRALPGPAQ------PPPLPQSP 63
            ::..|..||.       ...|.|..||.|...::....|    ..|..|.|      |||:...|
Mouse     1 MASQPPPPPKPWESRRIPGAGPGPGSGPGPTYQSADLGP----TLLTRPGQPTLTRVPPPILPRP 61

  Fly    64 FQQT---------QQYGGFGSGYGGNNYGLGGYGGFNSGAFGYGGLGGFGSGLGSGFGSGYGYGG 119
            .|||         ..|..|.||||.  ||...||.::..::||.||
Mouse    62 SQQTGSNNVNTFRPAYSSFSSGYGA--YGNSFYGSYSPYSYGYNGL------------------- 105

  Fly   120 GYGGGYGGGFGGGYNRFGAMGENDAEQRFIYMAESSSRPAFQSIESLVSAIGNIASMLDSTFFAL 184
                        |:||...  ::....||:..||.|||.|||||||:|.|..:::.|:|:||.|:
Mouse   106 ------------GFNRLRV--DDLPPSRFVQQAEESSRGAFQSIESIVHAFASVSMMMDATFSAV 156

  Fly   185 TSSFRAILGVATNFVRLRSVFAQFWTTFAIFRGLNWMYRKILYWLRLSNLDPSSAAFKKAFAEAL 249
            .:||||:|.||.:|.||:..|.:.::.||:.|.:.::||::.:.:.|..    .:..:..:||
Mouse   157 YNSFRAVLDVANHFSRLKIHFTKVFSAFALVRTIRYLYRRLQWMMGLRR----GSENEDLWAE-- 215

  Fly   250 NENNGQARGAPNVPRKGNSPWPVLAFISFIFTAPYLIMKLLGTVTNTAQEEARNPAKWTA----P 310
            :|.......|.:........||:..|.:.|...||||.|||    :|..:|..:...|.:    .
Mouse   216 SEGTVACLSAEDQATNSAKSWPIFLFFAVILGGPYLIWKLL----STHNDEVTDNTNWASGEDDH 276

  Fly   311 IQTQAVYEFVARSPSELSLRAGQMLHVAPRDIQQTLNLLNTGWALATTNGQTSGIIPISYVK--S 373
            :..:|.|:|||.|..|:|.|||.||::|.::.|..:.    ||.||:.:|||:|:||.:|||  .
Mouse   277 VVARAEYDFVAVSDEEISFRAGDMLNLALKEQQPKVR----GWLLASLDGQTTGLIPANYVKILG 337

  Fly   374 PQQMRQEMQDQTKPAQPQ----PELMNLSAGAFASPPL-EQQMNYDFNLAAQQQAPLGPPST 430
            .::.|:.::..|...|.|    |.|:.   |...:.|| ||:..::.......:....|.||
Mouse   338 KRRGRKTIESSTMLKQQQSFTNPTLIK---GVTTTNPLDEQEAAFESVFVETNKVSSAPDST 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pex13	NP_610850.1	Peroxin-13_N	140..290	CDD:282008	51/149 (34%)
Pex13	NP_610850.1	SH3_PEX13_eumet	312..373	CDD:212798	28/62 (45%)
Pex13	NP_076140.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..71		25/91 (27%)
		Peroxin-13_N	113..256	CDD:282008	45/142 (32%)
		SH3_PEX13_eumet	278..335	CDD:212798	20/60 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836046
Domainoid	1	1.000	92	1.000	Domainoid score	I7634
eggNOG	1	0.900	-	-		E1_KOG3875
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1967
Inparanoid	1	1.050	160	1.000	Inparanoid score	I4227
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46446
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005709
OrthoInspector	1	1.000	-	-		oto92502
orthoMCL	1	0.900	-	-		OOG6_105516
Panther	1	1.100	-	-	LDO	PTHR19332
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1291
SonicParanoid	1	1.000	-	-		X5398
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.790