DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pex13 and vav2

DIOPT Version :9

Sequence 1:	NP_610850.1	Gene:	Pex13 / 36462	FlyBaseID:	FBgn0033812	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	XP_021324720.1	Gene:	vav2 / 556413	ZFINID:	ZDB-GENE-091204-420	Length:	891	Species:	Danio rerio

Alignment Length:	108	Identity:	31/108 - (28%)
Similarity:	46/108 - (42%)	Gaps:	20/108 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   268 SPWPVLAFISFIFTAPYLIMKLLGTVTNTAQEEARNPAKWTAPIQTQAV--YEFVARSPSELSLR 330
            ||....|..:|.|.:|.       .:..::|..|...:.:|..:.:.||  |.|.||...|||||
Zfish   794 SPAATCASYNFSFLSPQ-------GLNFSSQSSAPFWSVFTPRVVSTAVARYNFAARDMRELSLR 851

  Fly   331 AGQMLHVAPRDIQQTLNLL--NTGWALATTNGQTSGIIPISYV 371
            .|        ||.:..:.:  :.||.....||:. |..|.:||
Zfish   852 EG--------DIVKIYSKIGGDQGWWKGEANGRI-GWFPSTYV 885

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pex13	NP_610850.1	Peroxin-13_N	140..290	CDD:282008	6/21 (29%)
Pex13	NP_610850.1	SH3_PEX13_eumet	312..373	CDD:212798	22/64 (34%)
vav2	XP_021324720.1	CAMSAP_CH	18..103	CDD:314792
		RhoGEF	211..386	CDD:238091
		PH_Vav	401..528	CDD:269930
		C1	536..579	CDD:237996
		SH3	601..660	CDD:327375
		SH2_Vav2	680..782	CDD:198269
		SH3_VAV2_2	832..889	CDD:212910	22/63 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1291
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.030