DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pex13 and pex13

DIOPT Version :9

Sequence 1:	NP_610850.1	Gene:	Pex13 / 36462	FlyBaseID:	FBgn0033812	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_956939.1	Gene:	pex13 / 393618	ZFINID:	ZDB-GENE-040426-1544	Length:	416	Species:	Danio rerio

Alignment Length:	413	Identity:	139/413 - (33%)
Similarity:	202/413 - (48%)	Gaps:	89/413 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 APLLPPSSSIG-VGVSSGGGYPPEAVLRTPYGNVRALPGPAQPPPLPQSPFQQTQQ--YGGFGSG 76
            |||...|:..| |..|...|..|..:.|.             .||:|..|.:|:.:  |..|.|.
Zfish    19 APLNYRSTDFGSVSQSGPSGSGPPVLTRV-------------VPPIPPRPVRQSYRPTYSSFPSS 70

  Fly    77 YGGNNYGLGGYGGFNSGAFGYGGLGGFGSGLGSGFGSGYGYGGGYGGGYGGGFGGGYNRFGAMGE 141
            |  :.||...|||::..::                 ||||.|||.          |||||..|.|
Zfish    71 Y--SPYGNSMYGGYSPYSY-----------------SGYGVGGGL----------GYNRFNTMDE 106

  Fly   142 NDAEQRFIYMAESSSRPAFQSIESLVSAIGNIASMLDSTFFALTSSFRAILGVATNFVRLRSVFA 206
             ....||:..||.|||.|||||||:|.|..:::.|:|:||.|:.:||||:|.||.:|.|||..|.
Zfish   107 -IPPSRFVQQAEESSRGAFQSIESIVHAFSSVSMMMDATFSAVYNSFRAVLDVANHFSRLRIHFT 170

  Fly   207 QFWTTFAIFRGLNWMYRKI--LYWLR----LSNLDPSSAAFKKAFAEALNENNGQARGA----PN 261
            :..:.||:.|.|.::||::  |..||    :.:|...|||.....:.:      .||||    |.
Zfish   171 KVLSAFALVRTLRYLYRRLQRLMGLRQGSEVDDLWADSAASSSVVSAS------GARGAGVEEPG 229

  Fly   262 VPRKGNS--PWPVLAFISFIFTAPYLIMKLLGTVTNTAQEEARNPAKWTA----PIQTQAVYEFV 320
            |    ||  .||:..|.:.:...||||.:||.:... |:|.|.|   |.:    .:..:..|:|.
Zfish   230 V----NSVKSWPIFLFFAVVLGGPYLIWRLLSSAEG-AEENATN---WASGEDDHVVARVEYDFT 286

  Fly   321 ARSPSELSLRAGQMLHVAPRDIQQTLNLLNTGWALATTNGQTSGIIPISYVKSPQQMR------- 378
            |.|..|:|::||.||::||::.|..:.    ||.||:.:|||:|::|.:|||...:.|
Zfish   287 AASEEEISVQAGDMLNLAPKEQQPRVR----GWLLASVDGQTTGLVPANYVKVLGRRRGRKHAEL 347

  Fly   379 QEMQDQTKPAQ--PQPELMNLSA 399
            :.|....:|||  |.|:...::|
Zfish   348 ERMAQAQEPAQNLPAPQTALITA 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pex13	NP_610850.1	Peroxin-13_N	140..290	CDD:282008	62/161 (39%)
Pex13	NP_610850.1	SH3_PEX13_eumet	312..373	CDD:212798	24/60 (40%)
pex13	NP_956939.1	Peroxin-13_N	108..256	CDD:282008	61/157 (39%)
pex13	NP_956939.1	SH3_PEX13_eumet	278..335	CDD:212798	24/60 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579499
Domainoid	1	1.000	94	1.000	Domainoid score	I7462
eggNOG	1	0.900	-	-		E1_KOG3875
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1967
Inparanoid	1	1.050	173	1.000	Inparanoid score	I4073
OMA	1	1.010	-	-		QHG46446
OrthoDB	1	1.010	-	-		D1085263at2759
OrthoFinder	1	1.000	-	-		FOG0005709
OrthoInspector	1	1.000	-	-		oto41190
orthoMCL	1	0.900	-	-		OOG6_105516
Panther	1	1.100	-	-	LDO	PTHR19332
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1291
SonicParanoid	1	1.000	-	-		X5398
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800