DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pex13 and Prex1

DIOPT Version :9

Sequence 1:NP_610850.1 Gene:Pex13 / 36462 FlyBaseID:FBgn0033812 Length:440 Species:Drosophila melanogaster
Sequence 2:NP_808450.2 Gene:Prex1 / 277360 MGIID:3040696 Length:1650 Species:Mus musculus


Alignment Length:290 Identity:66/290 - (22%)
Similarity:104/290 - (35%) Gaps:72/290 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   116 GYGGGYGGGYGGGFGGGYNRFGAM-----GENDAEQ----RFIYMAE--SSSRPAFQSIESLVSA 169
            |.|||.|||..||.|...:..|.:     ...|:|:    |...:.|  .:.|....::..|.||
Mouse     5 GSGGGDGGGDPGGDGAHPDARGPVSGPCAAARDSERQLRLRLCVLNEILGTERDYVGTLRFLQSA 69

  Fly   170 I-----GNIA-----SMLDSTFFALTSSFRAILGVATNFV---------------RLRSVFAQFW 209
            .     .|:|     .:.:.....|.|:...||.|..:|:               .|.:||.:|.
Mouse    70 FLQRIRQNVADSVEKGLTEENVKVLFSNIEDILEVHKDFLAALEYCLHPEPQSQHELGNVFLKFK 134

  Fly   210 TTFAIFRGLNWMYRKILYWLRLSNLDPSSAAFKKAFAEALNENNGQARGAPNVPRKGNSPWPVLA 274
            ..|.::......:.|.|..|...|..|:..||      .|:......|...::|.:|.    :|:
Mouse   135 DKFCVYEEYCSNHEKALRLLVELNKVPAVRAF------LLSCMLLGGRKTTDIPLEGY----LLS 189

  Fly   275 FISFIFTAPYLIMKL--------------------LGTVTNTAQEEARNPAKWTAPIQTQAVYEF 319
            .|..|...|.|:.:|                    :.||.:...|..|...|..|..|.|:..|.
Mouse   190 PIQRICKYPLLLKELAKRTPGKHPDHTAVQSALQAMKTVCSNINETKRQMEKLEALEQLQSHIEG 254

  Fly   320 VARSP-----SELSLRAGQMLHVAPRDIQQ 344
            ...|.     :||.|: |.:|.::..:||:
Mouse   255 WEGSNLTDICTELLLQ-GNLLKISAGNIQE 283

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Pex13NP_610850.1 Peroxin-13_N 140..290 CDD:282008 38/200 (19%)
SH3_PEX13_eumet 312..373 CDD:212798 11/38 (29%)
Prex1NP_808450.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..33 11/27 (41%)
RhoGEF 48..234 CDD:279015 37/195 (19%)
PH_Collybistin_ASEF 239..391 CDD:269931 13/46 (28%)
PH 267..384 CDD:278594 6/18 (33%)
DEP 409..489 CDD:295306
DEP_2_P-Rex 501..593 CDD:239887
PDZ 630..697 CDD:214570
PDZ 714..768 CDD:238080
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 793..813
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1022..1047
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1099..1129
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1291
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.030

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