DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pex13 and pex13

DIOPT Version :9

Sequence 1:	NP_610850.1	Gene:	Pex13 / 36462	FlyBaseID:	FBgn0033812	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_593611.1	Gene:	pex13 / 2543046	PomBaseID:	SPAC3C7.10	Length:	288	Species:	Schizosaccharomyces pombe

Alignment Length:	350	Identity:	80/350 - (22%)
Similarity:	124/350 - (35%)	Gaps:	113/350 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 PPLPQSPFQQTQQYGGFGSGYGGN----------------------NYGLGGYGGFNSGAFGYGG 99
            |.||..|      .||..|....|                      |.|...|.||||
pombe    10 PSLPSYP------AGGIMSVSNSNADTNQGVTQHPLANRIVNPNYYNMGFNPYSGFNS------- 61

  Fly   100 LGGFGSGLGSGFGSGYGYGGGYGGGYGGGFGGGYNRFGAMGENDAEQRFIYMAESSSRPAFQSIE 164
                                         |...:|.|..:..|        :..:....:.|.||
pombe    62 -----------------------------FIPSFNPFVPLETN--------LPGNGPISSLQVIE 89

  Fly   165 SLVSAIGNIASMLDSTFFALTSSFRAILGVATNFVRLRSVFAQFWTTFAIFRGLNWMYRKILYWL 229
            |:|.|:|:||.:|:||..|...|:...:.|:.|..:|:|   .....|.|...|:.:.|.:|.:.
pombe    90 SIVGAVGSIAQVLESTLMAAHMSYNTFVSVSENLNKLKS---SIGAIFGIVSLLSRLKRLVLKFF 151

  Fly   230 RLSNLDPSSAAFKKAFAEALNENNGQARGAPNVPRKGNSPWPV---LAFISFIFTAPYLIMKLLG 291
            :.|.:|..::.....|.:  .|.|.:           ||.:.:   ||.|..:...||.|::|..
pombe   152 KHSKIDEMNSQEYDVFEK--EEGNHK-----------NSIYSIVSSLAIILGLVGLPYAIIRLFK 203

  Fly   292 TVTNTAQEEARNPAKWTAPIQT----QAVYEFVARSPS-ELSLRAGQMLHVAPRDIQQTLNLLNT 351
            .:..  :|:....||....|.:    :|.|||::|.|. |:||:.|        ||...|:..:|
pombe   204 NIYE--KEKQIQQAKIRKKIDSLEFCKADYEFMSRDPGVEMSLKKG--------DIIAILSKTDT 258

  Fly   352 ------GWALATTNGQTSGIIPISY 370
                  .|.....:|:| |..|.:|
pombe   259 QGNPCEWWQGRKRSGET-GWFPSNY 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pex13	NP_610850.1	Peroxin-13_N	140..290	CDD:282008	37/152 (24%)
Pex13	NP_610850.1	SH3_PEX13_eumet	312..373	CDD:212798	19/69 (28%)
pex13	NP_593611.1	Peroxin-13_N	86..202	CDD:282008	36/131 (27%)
pex13	NP_593611.1	SH3_Pex13p_fungal	226..285	CDD:212705	19/65 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	42	1.000	Domainoid score	I3677
eggNOG	1	0.900	-	-		E1_KOG3875
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005709
OrthoInspector	1	1.000	-	-		oto100740
orthoMCL	1	0.900	-	-		OOG6_105516
Panther	1	1.100	-	-	LDO	PTHR19332
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1291
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.840