DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pex13 and Plekhg1

DIOPT Version :9

Sequence 1:	NP_610850.1	Gene:	Pex13 / 36462	FlyBaseID:	FBgn0033812	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	XP_006512502.1	Gene:	Plekhg1 / 213783	MGIID:	2676551	Length:	1487	Species:	Mus musculus

Alignment Length:	166	Identity:	35/166 - (21%)
Similarity:	57/166 - (34%)	Gaps:	42/166 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   269 PWPVLAFISFIFTAPYLIMKLLGTVTNTAQEE-------------------ARNPAKWTAPIQTQ 314
            |...|:|..|.:..|    ||..||...:|::                   |:.|||     ..|
Mouse   472 PKEPLSFSVFHYKNP----KLQHTVQAKSQQDKRLWVLHLKRLILENHAAAAKIPAK-----AKQ 527

  Fly   315 AVYEFVA-------RSP-SELSLRAGQMLHVAPRDIQQTLNLLNTGWALATTNGQTSGIIPISYV 371
            |:.|..|       .|| .|:....|.    ||..:::.....:....:..|:..:..|..:|..
Mouse   528 AILEMDAIHYPGFCYSPEGEMKTPCGS----APHRLRRKSEPSSRSHKVLKTSETSQDIQKVSRE 588

  Fly   372 KSPQQMRQEMQDQTKPAQPQPELMNL--SAGAFASP 405
            :||.|:...:..|.........::|:  ..|...||
Mouse   589 ESPSQLTSAVPAQRNCQPGSAAVINMLRGGGGVRSP 624

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pex13	NP_610850.1	Peroxin-13_N	140..290	CDD:282008	6/20 (30%)
Pex13	NP_610850.1	SH3_PEX13_eumet	312..373	CDD:212798	13/68 (19%)
Plekhg1	XP_006512502.1	RhoGEF	211..387	CDD:238091
Plekhg1	XP_006512502.1	PH_PLEKHG1_G2_G3	369..514	CDD:270063	10/45 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1291
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030