DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pex13 and Plekhg2

DIOPT Version :9

Sequence 1:NP_610850.1 Gene:Pex13 / 36462 FlyBaseID:FBgn0033812 Length:440 Species:Drosophila melanogaster
Sequence 2:XP_006539499.1 Gene:Plekhg2 / 101497 MGIID:2141874 Length:1366 Species:Mus musculus


Alignment Length:298 Identity:63/298 - (21%)
Similarity:100/298 - (33%) Gaps:123/298 - (41%)


- Green bases have known domain annotations that are detailed below.


  Fly   231 LSNLDPSSAAFKKAFAEALNENNGQARGAPNVPRKGNSP-WPVLAFISFIFTAPYLIMKLLGTVT 294
            |..|:.|||| :.....:|.:...:....|.:|   .:| .|.|:.||.:|..|.|      :.|
Mouse   635 LEGLEGSSAA-EIPCIPSLTDIPSEVPSLPEIP---EAPCLPCLSDISGVFEVPCL------SPT 689

  Fly   295 NTAQE---EARNPA----KW-TAPIQTQAVYEFVAR-------------SPSE------------ 326
            :|..:   .|..|:    .| ..|:|..|..:...|             ||||            
Mouse   690 STVPDIPSLATTPSFPCGSWLPGPLQEAAQPQATRRELLSGSNPGRLSESPSESREGQEDDTEGV 754

  Fly   327 ----LSLRAGQMLHVAPRDIQ-QTLNLLNTGW-AL------------------------ATTNGQ 361
                :...||..:...|.::: ::.:.:.:.| ||                        .:|:|:
Mouse   755 SFSAVQREAGTSVQGFPEELEYRSCSEIRSAWQALEQGQLARPGFPEPLLILEDSDLRGGSTSGK 819

  Fly   362 TSGIIPIS-------------YVKSPQQM-RQEMQDQT-----KP---AQPQPELMNLSAGAFAS 404
            |.  :|.|             |.:..||| |.|.:..|     :|   |||||.         ..
Mouse   820 TG--MPHSERSASRVRELARLYSERIQQMQRAETRASTNAPRRRPRVLAQPQPS---------PC 873

  Fly   405 PPLEQ---------------QMNYDFNLAAQQQAPLGP 427
            ||.|:               ::.:..| ..|:..||||
Mouse   874 PPQEEAEPGALPAFGHVLVCELAFPLN-CTQESVPLGP 910

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Pex13NP_610850.1 Peroxin-13_N 140..290 CDD:282008 17/59 (29%)
SH3_PEX13_eumet 312..373 CDD:212798 19/128 (15%)
Plekhg2XP_006539499.1 RhoGEF 103..278 CDD:366202
PH_PLEKHG1_G2_G3 260..410 CDD:270063
PTZ00449 <351..742 CDD:185628 28/116 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1291
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.030

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