DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dp and DPB

DIOPT Version :9

Sequence 1:	NP_477039.1	Gene:	Dp / 36461	FlyBaseID:	FBgn0011763	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	NP_850757.1	Gene:	DPB / 831847	AraportID:	AT5G03415	Length:	385	Species:	Arabidopsis thaliana

Alignment Length:	408	Identity:	137/408 - (33%)
Similarity:	194/408 - (47%)	Gaps:	100/408 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 TGSSA----------RNSGSASGIGNVGRMGAFSQMGSQGQFIRLQDNGLSIPKTEAGTTYTTVS 104
            |||::          .|:.|....|......:.|..||.|......:..:::..:.:.||:..::
plant     4 TGSNSNHNHHESNNNNNNPSTRSWGTAVSGQSVSTSGSMGSPSSRSEQTITVVTSTSDTTFQRLN 68

  Fly   105 AQKTSGAGSGHYDLPLKGDRYVKFTPNPIKMKSKLHAIQSNSLHSMSASSSSVQRKRK------P 163
                        :|.::||                        .:.|..:|.|::|::      |
plant    69 ------------NLDIQGD------------------------DAGSQGASGVKKKKRGQRAAGP 97

  Fly   164 DKAGKGLRHFSMKVCEKVEEKGKTTYNEVADDLVSE-EMKNN----AYDNNCDQKNIRRRVYDAL 223
            ||.|:|||.||||||||||.||:||||||||:||:| .:.||    ......|:|||||||||||
plant    98 DKTGRGLRQFSMKVCEKVESKGRTTYNEVADELVAEFALPNNDGTSPDQQQYDEKNIRRRVYDAL 162

  Fly   224 NVLMAINVISKDKKEIRWIGLPANSTETFLALEEENCQRRERIKQKNEMLREMIMQHVAFKGLVE 288
            |||||:::||||||||:|.|||..|......|:.|....|.||::|....:|:..|:|..:.|::
plant   163 NVLMAMDIISKDKKEIQWRGLPRTSLSDIEELKNERLSLRNRIEKKTAYSQELEEQYVGLQNLIQ 227

  Fly   289 RNKRNESQGVVPSPNASIQLPFIIVNTHKSTKINCSVTNDKSEYIFKFDKT-FEMHDDIEVLKRM 352
            ||:...|.|..||  ..:.||||:|.|.....:...::.|.....|.|:.| ||:|||..|||.|
plant   228 RNEHLYSSGNAPS--GGVALPFILVQTRPHATVEVEISEDMQLVHFDFNSTPFELHDDNFVLKTM 290

  Fly   353 GFL-------LGLDKGE--C---TPENIERVKSWVPPNLAKYVEAYGTGKTGE-NMYESDDEDNE 404
            .|.       .|.:..:  |   ||||         ||     :...||.|.: :|||:
plant   291 KFCDQPPQQPNGRNNSQLVCHNFTPEN---------PN-----KGPSTGPTPQLDMYET------ 335

  Fly   405 FNGYLESANESQGFAQHS 422
               :|    :||...|||
plant   336 ---HL----QSQQHQQHS 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dp	NP_477039.1	E2F_TDP	167..243	CDD:280479	55/80 (69%)
		coiled coil	248..294	CDD:271217	13/45 (29%)
		DP	255..388	CDD:285934	44/145 (30%)
DPB	NP_850757.1	E2F_TDP	101..182	CDD:280479	55/80 (69%)
		coiled coil	187..233	CDD:271217	13/45 (29%)
		DP	189..>295	CDD:285934	36/107 (34%)
		Neural_ProG_Cyt	276..>320	CDD:284080	19/57 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	108	1.000	Domainoid score	I2163
eggNOG	1	0.900	-	-		E1_KOG2829
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	180	1.000	Inparanoid score	I1460
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1046304at2759
OrthoFinder	1	1.000	-	-		FOG0002399
OrthoInspector	1	1.000	-	-		otm2801
orthoMCL	1	0.900	-	-		OOG6_102647
Panther	1	1.100	-	-	LDO	PTHR12548
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1414
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.830