DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fsn and spsb4b

DIOPT Version :9

Sequence 1:	NP_610849.1	Gene:	Fsn / 36460	FlyBaseID:	FBgn0043010	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_001003474.1	Gene:	spsb4b / 445080	ZFINID:	ZDB-GENE-040801-213	Length:	281	Species:	Danio rerio

Alignment Length:	181	Identity:	84/181 - (46%)
Similarity:	112/181 - (61%)	Gaps:	14/181 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 HAWSPNDCSRNVYIKPNG-FTLHRNPVAQSTDAARGKIGFRHGRHTWEVIWEGPL---GTVAVIG 141
            |||:|:|.|.|::||.:. .|.||:|||||||..|||.||..|.|.|.:.|  |:   ||.||:|
Zfish    57 HAWNPDDRSPNLFIKDDDRLTFHRHPVAQSTDCVRGKTGFTRGLHAWSLRW--PVRQRGTHAVVG 119

  Fly   142 ISTKEAALQCHGYVALLGSDDQSWGWNLVENHLLHNGDMQGS----YPLL----NNAPKYQVGER 198
            ::|..|.|:..||.||:|||.:||||:|....|.|:...:..    ||..    :....:.|.|.
Zfish   120 VATSLATLRAVGYSALVGSDAESWGWDLGRGRLYHDRKSRSGPAPPYPEFVEDEDEEGTFSVPEE 184

  Fly   199 IRVILDCEDNTLSFEKNYEFLGVAFRGLPDKKLYPTVSAVYGNTEVSMVYL 249
            |.|:||.::.||.|..:..:||||||||..|:|||.||||:|:.||||.|:
Zfish   185 ILVVLDMDEGTLGFCADGNYLGVAFRGLKGKRLYPIVSAVWGHCEVSMNYI 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fsn	NP_610849.1	F-box-like	13..54	CDD:289689
Fsn	NP_610849.1	SPRY_Fbox	81..255	CDD:293964	84/181 (46%)
spsb4b	NP_001003474.1	SPRY_SOCS1-2-4	57..235	CDD:293963	83/179 (46%)
spsb4b	NP_001003474.1	SOCS_SSB4	240..281	CDD:239712
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3953
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810