DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fsn and Spsb1

DIOPT Version :9

Sequence 1:	NP_610849.1	Gene:	Fsn / 36460	FlyBaseID:	FBgn0043010	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_001101464.1	Gene:	Spsb1 / 313722	RGDID:	1309319	Length:	273	Species:	Rattus norvegicus

Alignment Length:	193	Identity:	86/193 - (44%)
Similarity:	120/193 - (62%)	Gaps:	10/193 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 DLLASVS--TYKTKLRAYFHAWSPNDCSRNVYIKPNG-FTLHRNPVAQSTDAARGKIGFRHGRHT 125
            |||..:.  :|..:|   .|:|:.||.|.||::|.:. ...||:||||||||.|||:|:..|.|.
  Rat    38 DLLLDMPPVSYDVQL---LHSWNNNDRSLNVFVKEDDKLIFHRHPVAQSTDAIRGKVGYTRGLHV 99

  Fly   126 WEVIWE-GPLGTVAVIGISTKEAALQCHGYVALLGSDDQSWGWNLVENHLLHNGDMQGS--YP-L 186
            |::.|. ...||.||:|::|.:|.|...||..|:|::.:||||:|..|.|.|:|..|.|  || .
  Rat   100 WQITWAMRQRGTHAVVGVATADAPLHSVGYTTLVGNNHESWGWDLGRNRLYHDGKNQPSKTYPAF 164

  Fly   187 LNNAPKYQVGERIRVILDCEDNTLSFEKNYEFLGVAFRGLPDKKLYPTVSAVYGNTEVSMVYL 249
            |.....:.|.:...|.||.:|.||||..:.:::|||||||..|||||.||||:|:.|:.|.|:
  Rat   165 LEPDETFIVPDSFLVALDMDDGTLSFIVDGQYMGVAFRGLKGKKLYPVVSAVWGHCEIRMRYV 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fsn	NP_610849.1	F-box-like	13..54	CDD:289689
Fsn	NP_610849.1	SPRY_Fbox	81..255	CDD:293964	81/174 (47%)
Spsb1	NP_001101464.1	SPRY_SOCS1-2-4	54..227	CDD:293963	80/172 (47%)
Spsb1	NP_001101464.1	SOCS	232..273	CDD:413360
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3953
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810