DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fsn and Fbxo45

DIOPT Version :9

Sequence 1:	NP_610849.1	Gene:	Fsn / 36460	FlyBaseID:	FBgn0043010	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	XP_017453712.2	Gene:	Fbxo45 / 288042	RGDID:	1311861	Length:	289	Species:	Rattus norvegicus

Alignment Length:	244	Identity:	174/244 - (71%)
Similarity:	204/244 - (83%)	Gaps:	1/244 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 VLEVIFSYLELDDLSHCSQVCKSWYHFLN-DENSDVWRWHCLNKLPKESLKSDLLASVSTYKTKL 76
            |||::||||||.:|..|:.|||.||..|: ||||:|||..|...|.:|:|::|:|.::.:||.|:
  Rat    46 VLELVFSYLELSELRSCALVCKHWYRCLHGDENSEVWRSLCARSLAEEALRTDILCNLPSYKAKV 110

  Fly    77 RAYFHAWSPNDCSRNVYIKPNGFTLHRNPVAQSTDAARGKIGFRHGRHTWEVIWEGPLGTVAVIG 141
            ||:.||:|.||||||||||.|||||||||:|||||.||.||||..|||.|||.||||||||||||
  Rat   111 RAFQHAFSTNDCSRNVYIKKNGFTLHRNPIAQSTDGARTKIGFSEGRHAWEVWWEGPLGTVAVIG 175

  Fly   142 ISTKEAALQCHGYVALLGSDDQSWGWNLVENHLLHNGDMQGSYPLLNNAPKYQVGERIRVILDCE 206
            |:||.|.:||.||||||||||||||||||:|:|||||::.||:|..|||||||:|||||||||.|
  Rat   176 IATKRAPMQCQGYVALLGSDDQSWGWNLVDNNLLHNGEVNGSFPQCNNAPKYQIGERIRVILDME 240

  Fly   207 DNTLSFEKNYEFLGVAFRGLPDKKLYPTVSAVYGNTEVSMVYLGTPLDG 255
            |.||:||:.||||||||||||...|||.||||||||||::||||.||||
  Rat   241 DKTLAFERGYEFLGVAFRGLPKACLYPAVSAVYGNTEVTLVYLGKPLDG 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fsn	NP_610849.1	F-box-like	13..54	CDD:289689	25/41 (61%)
Fsn	NP_610849.1	SPRY_Fbox	81..255	CDD:293964	137/173 (79%)
Fbxo45	XP_017453712.2	F-box-like	41..86	CDD:403981	24/39 (62%)
Fbxo45	XP_017453712.2	SPRY_Fbox	115..289	CDD:293964	137/173 (79%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	210	1.000	Domainoid score	I2732
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H14713
Inparanoid	1	1.050	344	1.000	Inparanoid score	I2261
OMA	1	1.010	-	-		QHG45658
OrthoDB	1	1.010	-	-		D1027590at2759
OrthoFinder	1	1.000	-	-		FOG0007019
OrthoInspector	1	1.000	-	-		oto98772
orthoMCL	1	0.900	-	-		OOG6_107936
Panther	1	1.100	-	-	LDO	PTHR12245
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5114
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.980