DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fsn and spsb-1

DIOPT Version :9

Sequence 1:	NP_610849.1	Gene:	Fsn / 36460	FlyBaseID:	FBgn0043010	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_497321.3	Gene:	spsb-1 / 266876	WormBaseID:	WBGene00021597	Length:	483	Species:	Caenorhabditis elegans

Alignment Length:	175	Identity:	79/175 - (45%)
Similarity:	113/175 - (64%)	Gaps:	4/175 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 HAWSPNDCSRNVYIK-PNGFTLHRNPVAQSTDAARGKIGFRHGRHTWEVIW-EGPLGTVAVIGIS 143
            |:|:|.|.|.|:::| .:.||.||:|||||||..|||:|:..|.|.|::.| |...||.||:|::
Worm   131 HSWNPEDRSLNIFVKDEDKFTFHRHPVAQSTDCIRGKMGYSRGFHVWQIEWPERQRGTHAVVGVA 195

  Fly   144 TKEAALQCHGYVALLGSDDQSWGWNLVENHLLHNG--DMQGSYPLLNNAPKYQVGERIRVILDCE 206
            ||.|.|...||.||:|:.|:|:||::......|:.  .|...||..|:...|.|.::...|||.:
Worm   196 TKNAPLHAAGYTALIGTTDESYGWDITRRECHHDSKHTMTWRYPFSNSRDVYNVPDKFYCILDMD 260

  Fly   207 DNTLSFEKNYEFLGVAFRGLPDKKLYPTVSAVYGNTEVSMVYLGT 251
            :..::|..:.||||||||.|..|.|||.|:||:|:.|:||.|||:
Worm   261 EGYMAFATDDEFLGVAFRNLKGKTLYPIVAAVWGHCEISMRYLGS 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fsn	NP_610849.1	F-box-like	13..54	CDD:289689
Fsn	NP_610849.1	SPRY_Fbox	81..255	CDD:293964	79/175 (45%)
spsb-1	NP_497321.3	SPRY_SOCS1-2-4	131..303	CDD:293963	76/171 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910