Protein Alignment Fsn and FBXO45

DIOPT Version :10

• Sequence 1: NP_610849.1
• Gene: Fsn / 36460
• FlyBaseID: FBgn0043010
• Length: 255
• Species: Drosophila melanogaster
• Sequence 2: NP_001099043.1
• Gene: FBXO45 / 200933
• HGNCID: 29148
• Length: 286
• Species: Homo sapiens
• Alignment Length: 244
• Identity: 174/244 - (71%)
• Similarity: 204/244 - (83%)
• Gaps: 1/244 - (0%)

  Fly    13 VLEVIFSYLELDDLSHCSQVCKSWYHFLN-DENSDVWRWHCLNKLPKESLKSDLLASVSTYKTKL 76
            |||::||||||.:|..|:.|||.||..|: ||||:|||..|...|.:|:|::|:|.::.:||.|:
Human    43 VLELVFSYLELSELRSCALVCKHWYRCLHGDENSEVWRSLCARSLAEEALRTDILCNLPSYKAKI 107

  Fly    77 RAYFHAWSPNDCSRNVYIKPNGFTLHRNPVAQSTDAARGKIGFRHGRHTWEVIWEGPLGTVAVIG 141
            ||:.||:|.||||||||||.|||||||||:|||||.||.||||..|||.|||.||||||||||||
Human   108 RAFQHAFSTNDCSRNVYIKKNGFTLHRNPIAQSTDGARTKIGFSEGRHAWEVWWEGPLGTVAVIG 172

  Fly   142 ISTKEAALQCHGYVALLGSDDQSWGWNLVENHLLHNGDMQGSYPLLNNAPKYQVGERIRVILDCE 206
            |:||.|.:||.||||||||||||||||||:|:|||||::.||:|..|||||||:|||||||||.|
Human   173 IATKRAPMQCQGYVALLGSDDQSWGWNLVDNNLLHNGEVNGSFPQCNNAPKYQIGERIRVILDME 237

  Fly   207 DNTLSFEKNYEFLGVAFRGLPDKKLYPTVSAVYGNTEVSMVYLGTPLDG 255
            |.||:||:.||||||||||||...|||.||||||||||::||||.||||
Human   238 DKTLAFERGYEFLGVAFRGLPKVCLYPAVSAVYGNTEVTLVYLGKPLDG 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fsn	NP_610849.1	F-box_FBXO45	5..41	CDD:438883	16/27 (59%)
		SPRY_Fbox	81..255	CDD:293964	137/173 (79%)
FBXO45	NP_001099043.1	F-box_FBXO45	38..71	CDD:438883	16/27 (59%)
		SPRY_Fbox	112..286	CDD:293964	137/173 (79%)