DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4646 and CZIB

DIOPT Version :9

Sequence 1:NP_001286382.1 Gene:CG4646 / 36459 FlyBaseID:FBgn0033810 Length:163 Species:Drosophila melanogaster
Sequence 2:NP_060357.1 Gene:CZIB / 54987 HGNCID:26059 Length:160 Species:Homo sapiens


Alignment Length:161 Identity:74/161 - (45%)
Similarity:104/161 - (64%) Gaps:3/161 - (1%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MVRVGLQISATLENVDKLETSHPDYSFFLKLKCSNCGEQSDKWHDITESERVQ-QDSRNAAGFNF 64
            |.::.||:.|||||:..|.....|:.::||:||.||||.||||..|...:.|. :..|.:|  :.
Human     1 MGKIALQLKATLENITNLRPVGEDFRWYLKMKCGNCGEISDKWQYIRLMDSVALKGGRGSA--SM 63

  Fly    65 FMKCKMCSRENSIDIVDKSNAPYTADDSGAFKTIVVFECRGAEPVEFSPRVGWRVSSAENGQQFE 129
            ..|||:|:|||||:|:..:..||.|:|:..|||||.|||||.|||:|.|:.|:.....|:|..|.
Human    64 VQKCKLCARENSIEILSSTIKPYNAEDNENFKTIVEFECRGLEPVDFQPQAGFAAEGVESGTAFS 128

  Fly   130 EVDLSEDDWVEYDQKNNNSVGIYEFASKFIK 160
            :::|.|.||.:||:|...||||||...:|:|
Human   129 DINLQEKDWTDYDEKAQESVGIYEVTHQFVK 159

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4646NP_001286382.1 DUF866 6..158 CDD:283540 71/152 (47%)
CZIBNP_060357.1 DUF866 6..157 CDD:399121 71/152 (47%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165159207
Domainoid 1 1.000 151 1.000 Domainoid score I4357
eggNOG 1 0.900 - - E1_KOG1296
Hieranoid 1 1.000 - -
Homologene 1 1.000 - - H41206
Inparanoid 1 1.050 157 1.000 Inparanoid score I4293
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG55802
OrthoDB 1 1.010 - - D1398309at2759
OrthoFinder 1 1.000 - - FOG0004899
OrthoInspector 1 1.000 - - oto89956
orthoMCL 1 0.900 - - OOG6_102587
Panther 1 1.100 - - LDO PTHR12857
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2340
SonicParanoid 1 1.000 - - X3456
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
1615.800

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