Protein Alignment CG4630 and SLC22A13

DIOPT Version :10

• Sequence 1: NP_001260948.1
• Gene: CG4630 / 36458
• FlyBaseID: FBgn0033809
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_004247.2
• Gene: SLC22A13 / 9390
• HGNCID: 8494
• Length: 551
• Species: Homo sapiens
• Alignment Length: 582
• Identity: 176/582 - (30%)
• Similarity: 279/582 - (47%)
• Gaps: 83/582 - (14%)

  Fly    15 FDDILVEIGEFGRFQRRNYLLICLPVLFAAANSLSYVFTAGSPTYRCYVPECDKLVDAEYGANWV 79
            |..:|.|||:|||||.:..:|:|:....:.....::||......:.|.|
Human     4 FVQVLAEIGDFGRFQIQLLILLCVLNFLSPFYFFAHVFMVLDEPHHCAV---------------- 52

  Fly    80 SIAVPGSWSKRGHFTPSTCERFVAN-----GDHLESS---SDPWSAWPLDQCFAENFTTETERCN 136
                  :|.|...|..|..|:.|.:     ..|.|..   ..|.:...|....:..| .||:.|:
Human    53 ------AWVKNHTFNLSAAEQLVLSVPLDTAGHPEPCLMFRPPPANASLQDILSHRF-NETQPCD 110

  Fly   137 Q-FVYGSSE-RTIVQQWGLQCPENLWKLAFVGTIHFAGLVVGTALSGYLADRYGRKHIFLFCIVF 199
            . :.|..:. .::..::.|.|.....| ....::..|||:|||.:.|.|.||.|||...|..::.
Human   111 MGWEYPENRLPSLKNEFNLVCDRKHLK-DTTQSVFMAGLLVGTLMFGPLCDRIGRKATILAQLLL 174

  Fly   200 MALTGVAQALSWDYISF-LFFALLNAVGTSGVYPLAF---IIGVEMVGPRKREMSSIVLNYFYAV 260
            ..|.|:|.|.   ..|| |:.||..||.|: |..|:|   .:..|.|||..|..:.::....:::
Human   175 FTLIGLATAF---VPSFELYMALRFAVATA-VAGLSFSNVTLLTEWVGPSWRTQAVVLAQCNFSL 235

  Fly   261 GEALL-GLSVFLPDWRQLQLALSVPPLICVAYFWLVPESVRWLLARNRREQAGVIIRRAAKVNRR 324
            |:.:| ||:....:||.||:..:.|.|:...|||.:|||.||||.|.|.::|..:|::||.||||
Human   236 GQMVLAGLAYGFRNWRLLQITGTAPGLLLFFYFWALPESARWLLTRGRMDEAIQLIQKAASVNRR 300

  Fly   325 DISVELMASFKQQELDAETGQEDDVEGGLHVKKDDKIWLAVKEVARSHILMGRYAILLLIWAVNA 389
            .:|.|||    .|.:..:||...:                ..::.|...|.....|:..:|.|::
Human   301 KLSPELM----NQLVPEKTGPSGN----------------ALDLFRHPQLRKVTLIIFCVWFVDS 345

  Fly   390 IVYYGLSLNATSLSGNKYLNFALVCLVEIPGYSLAWLFLRRFGRRVALSGSLLLCSITCVASGFV 454
            :.||||||.......:.||...:...||:|....:...::||||:.:..|:|:|..:.|:...|
Human   346 LGYYGLSLQVGDFGLDVYLTQLIFGAVEVPARCSSIFMMQRFGRKWSQLGTLVLGGLMCIIIIF- 409

  Fly   455 TLAQGDWIPCQTGVESRHSWSCANWLVVTLFLVGKLGITSSFAVIYTFTAEMMPTVIRSGGVGVM 519
                   ||....|           :|..|.:|||:...::|.:.|.::||:.||::|..|:|::
Human   410 -------IPADLPV-----------VVTMLAVVGKMATAAAFTISYVYSAELFPTILRQTGMGLV 456

  Fly   520 STFARFGAMLAPFVPLLASYYDPLPLLLFGTLSLVAGLLSLLLPETFNRKLPDTVEEAIALG 581
            ..|:|.|.:|.|.|.||..|:..||:|::|:|.:|||||..|||||..:.|.||::: :.||
Human   457 GIFSRIGGILTPLVILLGEYHAALPMLIYGSLPIVAGLLCTLLPETHGQGLKDTLQD-LELG 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4630	NP_001260948.1	2A0119	23..573	CDD:273328	168/564 (30%)
SLC22A13	NP_004247.2	MFS_OAT	102..500	CDD:340932	141/442 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	511..551		2/8 (25%)