Protein Alignment CG4630 and TPO4

DIOPT Version :10

• Sequence 1: NP_001260948.1
• Gene: CG4630 / 36458
• FlyBaseID: FBgn0033809
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_014916.1
• Gene: TPO4 / 854447
• SGDID: S000005799
• Length: 659
• Species: Saccharomyces cerevisiae
• Alignment Length: 614
• Identity: 119/614 - (19%)
• Similarity: 199/614 - (32%)
• Gaps: 235/614 - (38%)

  Fly    95 PSTCERFVANGDHLESSS---------------------------------------DP-----W 115
            |...::.|.|..:|:|:|                                       ||     |
Yeast    22 PKALDKNVTNSGNLDSTSSSTGSITEDEKRSEPNADSNNMTGGEPIDPRDLDWDGPDDPDNPHNW 86

  Fly   116 SA---WPLDQCFAENFTTETER--CNQFVYGSS----------ERTIVQQWGLQCPENLWKLAFV 165
            |:   |         :||.|..  |.....|||          ||..|.|          .||..
Yeast    87 SSLKKW---------YTTMTSAFLCLVVTMGSSLYVSSVPELVERYHVSQ----------TLALA 132

  Fly   166 G-TIHFAGLVVGTALSGYLADRYGRKHIFLFCIVFMALTGVAQALSWDYISFLFFALLNAVGTSG 229
            | |.:..||  .|.:...|::.:|||.::||.:.               :|.||   ...||.|.
Yeast   133 GLTFYLLGL--STVIGAPLSEVFGRKPVYLFSLP---------------VSMLF---TMGVGLSN 177

  Fly   230 -----VYPLAFIIGVEMVGPRKREMSSIVLNYF----YAVGEALLGLSVFL-------------- 271
                 :.||.|:.|| ...|.....|..:|:.|    .:|......||.||
Yeast   178 GHMRIILPLRFLSGV-FASPALSVGSGTILDIFDVDQVSVAMTYFVLSPFLGPVLSPIMAGFATE 241

  Fly   272 ------PDWRQLQLALSVPPLICVAYFWLVPESVRWLLARNRREQAGVIIRRAAKVNRRDISVEL 330
                  .:|.||.....:.|.|.     |:||:           ..|:|:|:.||  :|:|:::.
Yeast   242 AKGWRWSEWIQLIAGGLILPFIA-----LMPET-----------HKGIILRKRAK--KRNIALKK 288

  Fly   331 MASFKQQELDAETGQEDDVEGGLHVKKDDKIWLAVKEV--ARSHILMGRYAILLLIWAVNAIVYY 393
            .:...|:|....|..       :.:.:..|: |.|:.:  ..|..:...:|||...:...|::|.
Yeast   289 FSREAQKEFLKTTVT-------ITILRPLKM-LVVEPIVFVFSVYVAFIFAILFGFFEAYAVIYR 345

  Fly   394 GLSLNATSLSGNKYLNFALVCLVEIPGYSL---AWLFL---RRF--------------------- 431
            |:...:..:||..::..         |..|   |:.:|   |::
Yeast   346 GVYHMSMGISGLPFIGI---------GVGLWIGAFFYLYIDRKYLFPKPPAGTQPLTEKERTSKR 401

  Fly   432 -----GRRVALSGSLLLCSITCVASGFVTLAQGDWIPCQTGVESR------HSW---SCANWLVV 482
                 |.|.|.:|.||    ..|...|:       |.|:.|..:.      .:|   |..:|:..
Yeast   402 TTPYRGARDAETGELL----PVVPEKFL-------IACKFGSVALPIGLFWQAWTARSDVHWMAP 455

  Fly   483 TLFLVGKLGITSSFAVIYTFTAEMM-------PTVIRSGGVGVMSTFARFGAMLAPFVPLLA-SY 539
            .     ..|:...|.:|..|.:.:|       |..:.|  ....:...|:  :::...||.. ..
Yeast   456 V-----AAGVPFGFGLILIFFSVLMYFSTCYPPLTVAS--CLAANNLLRY--VMSSVFPLFTIQM 511

  Fly   540 YDPLPLLLFGTLSLVAGLLSLLLPETFNR 568
            |..:.:....||..:..::.:.:|..|.:
Yeast   512 YTKMKIKWASTLFALVCVVMIPIPWVFEK 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4630	NP_001260948.1	2A0119	23..573	CDD:273328	119/614 (19%)
TPO4	NP_014916.1	MFS_Tpo1_MDR_like	95..546	CDD:340881	107/532 (20%)