DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4630 and OCT3

DIOPT Version :9

Sequence 1:	NP_001260948.1	Gene:	CG4630 / 36458	FlyBaseID:	FBgn0033809	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	NP_173089.1	Gene:	OCT3 / 838209	AraportID:	AT1G16390	Length:	518	Species:	Arabidopsis thaliana

Alignment Length:	563	Identity:	142/563 - (25%)
Similarity:	225/563 - (39%)	Gaps:	98/563 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 IGEFGRFQRRNYLLICLPVLFAAANSLSYVFTAGSPTYRCYVPECDKLVDAEYGANWVSIAVPGS 86
            ||:||..|.....|:.....|.|..:...|||...|.:.|  ...|: ||
plant    33 IGDFGWAQFLQAALVSFAWFFDAQQTFITVFTDSQPMWHC--DNSDR-VD--------------- 79

  Fly    87 WSKRGHFTPSTCERFVANGDHLESSSDPWSAWPLDQCFAENFTTETERCNQFVYGSSERTIVQQW 151
                     |.|....:|...|.:.:  || |.|               |..|      :|:.:|
plant    80 ---------SVCNTSSSNLCTLPNQT--WS-WDL---------------NPHV------SIISEW 111

  Fly   152 GLQCPENLWKLAFVGTIHFAG-LVVGTALSGYLADRYGRKHIFLFCIVFMALTGVAQALSWDYIS 215
            ||||..:..| .|..:..|.| |:.|.|||.......|||::.|...:.|:|:.:..|.|.....
plant   112 GLQCAGSFLK-GFPASSFFLGCLIGGLALSTLADSSLGRKNMLLLSCLIMSLSSMLTAFSTSIWV 175

  Fly   216 FLFFALLNAVGTSGVYPLAFIIGVEMVGPRKREMSSIVLNYFYAVGEALLGLSVFLPD---WRQL 277
            :.|...||..|.:.:...|.::..|:||.:.|.....:..:.:.:|...|.:..::.:   ||.|
plant   176 YAFLRFLNGCGRATIGTCALVLSTELVGKKWRGQVGAMGFFCFTLGFLSLPMLGYINEGNSWRNL 240

  Fly   278 QLALSVPPLI-CVAYFWLVPESVRWLLARNRREQAGVIIRRAAKVNRRDISVELMASFKQQELDA 341
            .:..|:|.|| |......|.||.|||:.:.|:|:|..|::..|       |..:..||.....:.
plant   241 YVWTSIPTLIYCCLVRSFVRESPRWLIVKGRKEEAVSILQSIA-------SNAITMSFTNLCFEV 298

  Fly   342 ETGQEDDVEGGLHVKKDDKIWLAVKEVARSHILMGRYAILLLIWAVNAIVYYGLSLNATSLSGNK 406
            |..|.         |.:..::.|:|.:.|......|....:::.....:||||:.|..|:|:.|.
plant   299 ENDQS---------KSNPDVYDALKILVRKSWSFRRLLAAMVVGFGIGMVYYGMPLALTNLNFNL 354

  Fly   407 YLNFALVCLVEIPGYSLAWLFLRRFGRRVALSGSLLLCSITCVASGFVTLAQGDWIPCQTGVESR 471
            ||......|.|.|.:.:.:.|:.:..||.||.|...|..|:  ::....|.|      |.|.
plant   355 YLGVVFNALSEFPAFLITFFFIDKINRRDALIGFTALSGIS--SALIAVLGQ------QLGS--- 408

  Fly   472 HSWSCANWLVVTLFLVGKLGITSSFAVIYTFTAEMMPTVIRSGGVGVMSTFARFGAMLAPFVPLL 536
                    |.:.|.||......::|.:...:|.||.||.:|:..:.::.....||.:   |.|::
plant   409 --------LQIVLELVSFFSACTAFNMTLIYTIEMFPTCVRNSAISMVRQALVFGGV---FSPVM 462

  Fly   537 ASYYDPLPLLLFGTLSLVAGLLSLL---LPETFNRKLPDTVEE 576
            .:.........:|...|:.||..|.   ||||....|.||::|
plant   463 VAAGRENQFWSYGLFGLIIGLCGLFVFGLPETRGSVLCDTMDE 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4630	NP_001260948.1	2A0119	23..573	CDD:273328	138/557 (25%)
CG4630	NP_001260948.1	MFS	158..533	CDD:119392	95/379 (25%)
OCT3	NP_173089.1	MFS_OCT_plant	87..492	CDD:340936	116/467 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I1021
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.070