DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4630 and OCT4

DIOPT Version :9

Sequence 1:	NP_001260948.1	Gene:	CG4630 / 36458	FlyBaseID:	FBgn0033809	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	NP_188702.2	Gene:	OCT4 / 821613	AraportID:	AT3G20660	Length:	526	Species:	Arabidopsis thaliana

Alignment Length:	572	Identity:	159/572 - (27%)
Similarity:	267/572 - (46%)	Gaps:	106/572 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LDFDDILVE-IGEFGRFQRRNYLLICLPVLFAAANSLSYVFTAGSPTYRCYVPECDKLVDAEYGA 76
            |..|::|.. .|||||:|.::::|.|:.....|.:::..:|....|.:||...:|.
plant    32 LCIDEMLQRYCGEFGRWQLKHFVLTCIAWALEAFHTMVMIFADQEPEWRCVGSDCR--------- 87

  Fly    77 NWVSIAVPGSWSKRGHFTPSTCERFVANGDHLESSSDPWSAWPLDQCFAENFTTETERCNQFVYG 141
                   .||.:         ||        |:.||..|:|..                     |
plant    88 -------VGSLN---------CE--------LDPSSWEWTAGK---------------------G 107

  Fly   142 SSERTIVQQWGLQCPENLWKLAFVGTIHFAGLVVGTALSGYLAD-RYGRKHIFLFCIVFMALTGV 205
            ||   .|.:|||.|.:. :|:..|..:.|||.::|..:.|:|:| :.|||.......:..|:.|:
plant   108 SS---TVSEWGLICGDK-YKVGLVQALFFAGCMIGAGVFGHLSDSKLGRKGSLTVVCIINAIFGI 168

  Fly   206 AQALSWDYISFLFFALLNAVGTSGVYPLAFIIGVEMVGPRKREMSSIVLNYFYAVGEALL-GLSV 269
            |.|.|.:|.:::....|....|.||...||::..|.:||.||.::.:...||::.|.|:| |::.
plant   169 ATAFSPNYWTYVVLRFLTGFSTGGVGLTAFVLATEPIGPSKRGVAGMSTFYFFSAGIAVLSGIAY 233

  Fly   270 FLPDWRQLQLALSVPPLICVAYFWL-----VPESVRWLLARNRREQAGVIIRRAAKVNRRDISVE 329
            ....||:|.:..|:|.|:    |.|     :.||.||.|.|.:.::|..::...||.|.|.|...
plant   234 VFRSWRELFIVSSLPSLL----FLLIVIPFISESPRWYLVRGKVDEAMKLMHSIAKTNGRHIPAG 294

  Fly   330 LMASFKQQELDAETGQEDDVEGGLHVKKDDKIWLAVKEVARSHILMGRYAILLLIWAVNAIVYYG 394
            :..:.           :||||.. :.:::..:..::|:|..|.::..|..|.:.|....:|||||
plant   295 VTLAL-----------DDDVENN-NGERNTAVEGSLKDVILSPLMRMRLVISVAISFTVSIVYYG 347

  Fly   395 LSLNATSLSGNKYLNFALVCLVEIPGYSLAWLFLRRFGRRVALSGSLLLCSITCVASGFVTLAQG 459
            ||||..:|..|.|||..:..:.|:|.:::..:.|.::||:....|:.....:.|:. ||.....|
plant   348 LSLNVGNLKTNLYLNVFVNAVSEMPAFAITAVLLDKYGRKPLSIGTQWFSCVFCLV-GFSVWGAG 411

  Fly   460 DW--IPCQTGVESRHSWSCANWLVVTLFLVGKLGITSSFAVIYTFTAEMMPTVIRSGGVGVMSTF 522
            .|  :...:||                  :|..|:..::.:::.:.||:.|||:|:..:|..:..
plant   412 PWKSVRMVSGV------------------LGIFGMAGTYNLLFIYIAELFPTVVRNAALGCATQA 458

  Fly   523 ARFGAMLAPFVPLLASYYDPLPLLLFGTLSLVAGLLSLLLPETFNRKLPDTV 574
            |:.||:|||||.:|.   :.||..:|....||.|.|:..||||.|:.|.||:
plant   459 AQMGAILAPFVVVLG---EELPFGVFAVCGLVGGGLAFYLPETLNKPLYDTM 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4630	NP_001260948.1	2A0119	23..573	CDD:273328	154/558 (28%)
CG4630	NP_001260948.1	MFS	158..533	CDD:119392	107/383 (28%)
OCT4	NP_188702.2	MFS_OCT_plant	90..496	CDD:340936	133/485 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I1021
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.060