DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4630 and LOC566640

DIOPT Version :9

Sequence 1:	NP_001260948.1	Gene:	CG4630 / 36458	FlyBaseID:	FBgn0033809	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	XP_009291426.1	Gene:	LOC566640 / 566640	-ID:	-	Length:	511	Species:	Danio rerio

Alignment Length:	567	Identity:	142/567 - (25%)
Similarity:	234/567 - (41%)	Gaps:	125/567 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 GRFQRRNYLLICLPVLFAAANSLSYVFTAG-SPTYRCYVPECDKLVDAEYGANWVSIAVPGSWSK 89
            |..|...:.::.||:.|.|......|||.. :|   |.|....|.::....:|   :::..||:
Zfish    13 GTLQIHVFAILTLPIFFTAFTFFVDVFTLHITP---CSVDIATKTLNRSVDSN---VSIFASWT- 70

  Fly    90 RGHFTPSTCERFVANGDHLESSSDPWSAWPLDQCFAENFTTETERCNQFVYGSSERTIVQQWGLQ 154
                               ::.|||.|:   ..|.         :.|.|.:|.:
Zfish    71 -------------------DNHSDPTSS---QTCL---------KANHFAHGQA----------- 93

  Fly   155 CPENLWKLAFVGTIHFAGLVVGTALSGYLADRYGRKHIFLFCIVFMALTGVAQALSWDYIS-FLF 218
                         .:..||::|:.:.|.|:|:||:|.:.:.|....|:..|..|. ..|:. :|.
Zfish    94 -------------TYMTGLLIGSLIGGALSDKYGKKILLICCTAIHAVATVIVAF-LPYVPVYLT 144

  Fly   219 FALLNAVGTSGVYPLAFIIGVEMVGPRKREMSSIVLNYFYAVGEALLGLSVFLPD-WRQLQLALS 282
            ...::.|....::...:.:|||...|:.|.....:.::.:::|...|....||.. |.|..|||.
Zfish   145 ARAISGVSCCAIHICTYSLGVEWSLPKYRIWPPTLFSFIFSLGMMGLAAVAFLSSTWIQFHLALG 209

  Fly   283 VPPLICVAYFWLVPESVRWLLARNRREQAGVIIRRAAKVNR-RDISVELMASFKQQELDAETGQE 346
            :|.::.:..::.:|||.||||...|.:.......|::|..| .|:.:..:.:..|:.|..::..|
Zfish   210 IPQILFLPLYFFLPESPRWLLLNKRMKTLESYQNRSSKDKRYLDLLLHSVDNEAQKSLSEKSSTE 274

  Fly   347 DDVEGGLHVKKDDKIWLAVKEVARSH-------ILMGRYAILLLIWAVNAIVYYGLSLNATSLSG 404
                                  .||:       |::.|..|:..|...:|:.|||:..:..|...
Zfish   275 ----------------------TRSNFTNFTSPIILLRLFIMSYIGFASALTYYGICFSIGSFGV 317

  Fly   405 NKYLNFALVCLVEIPGYSLAWLFLRRFGRRVALSGSLLLCSITCVASGFVTLAQGDWIPCQTGVE 469
            |.||......|.|.|...|.:| |:|:|||....|||.|..|:|:.|..|:..      |....
Zfish   318 NIYLAQFFSGLSEAPSLLLPFL-LKRWGRRPFTMGSLFLSGISCMLSLLVSKF------CNMPA- 374

  Fly   470 SRHSWSCANWLVVTLFLVGKLGITSSFAVIYTFTAEMMPTVIRSGGVGVMSTFAR----FGAMLA 530
                      ||:||.|:|||.:.|::.|...:..|:.|||||...|||:|...|    ..|:::
Zfish   375 ----------LVMTLALMGKLCMQSTYCVSTLYGIELFPTVIRQKCVGVVSLCYRVACIINAVMS 429

  Fly   531 PFVPLLASYYDPLPLLL-FGTLSLVAGLLSLLLPETFNRKLPDTVEE 576
            |...:      |||.:: :....::...|.||||||....|||||.|
Zfish   430 PEGGI------PLPAMISYSGGPIIGAALCLLLPETSGIPLPDTVHE 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4630	NP_001260948.1	2A0119	23..573	CDD:273328	138/562 (25%)
CG4630	NP_001260948.1	MFS	158..533	CDD:119392	102/388 (26%)
LOC566640	XP_009291426.1	MFS	93..455	CDD:119392	106/432 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010