Protein Alignment CG4630 and slc22a16

DIOPT Version :10

• Sequence 1: NP_001260948.1
• Gene: CG4630 / 36458
• FlyBaseID: FBgn0033809
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_001020659.1
• Gene: slc22a16 / 557279
• ZFINID: ZDB-GENE-041001-166
• Length: 565
• Species: Danio rerio
• Alignment Length: 589
• Identity: 174/589 - (29%)
• Similarity: 269/589 - (45%)
• Gaps: 75/589 - (12%)

  Fly    15 FDDILVEIGEFGRFQRRNYLLICLPVLFAAANSLSYVFTAGSPTYRCYVPECDKLVDAEY-GANW 78
            ||    |:|.|.|||...|.......:....:.|:.||...:|.:.|..|.  .:.|..| ..::
Zfish     9 FD----ELGHFKRFQACLYFAAIFQAISCGIHYLASVFLVETPKFLCNPPL--NITDVLYKNLSF 67

  Fly    79 VSIAVPGSWSKRGHFTPSTCERFV--ANGDHLESSSDPWSAWPLDQCF------AENFTTE---- 131
            .|:|  ..|:   |:........|  :.||.          |.|..|.      |.||..|
Zfish    68 TSLA--DIWT---HYKTGDGPVVVRTSQGDQ----------WELSPCLKALRLDAINFQYEFFGN 117

  Fly   132 --TERCNQFVYGSS--ERTIVQQWGLQCPENLWKLAFVGTIHFAGLVVGTALSGYLADRYGRKHI 192
              .|.|..|||..|  |::||..|.|.| |..|...........|:::|..:.|..|||.||:.:
Zfish   118 KSVESCGAFVYDHSEVEQSIVTDWDLVC-EREWLAKLTQPTFMLGVLIGALMFGDAADRIGRRPV 181

  Fly   193 FLFCIVFMALTGVAQALSWDYISFLFFALLNAVGTSGVYPLAFIIGVEMVGPRKREMSSIVLNYF 257
            .:...:...:.||..|.:.:|..|:....|.|..:||...:.|:...|..|.:.|..:|:.::..
Zfish   182 LMATSLCQFIFGVTVAFTGNYYLFVVMRFLLATVSSGYLVVVFVYVTEFTGIKVRTWTSMHVHAA 246

  Fly   258 YAVG---EALLGLSVFLPDW--RQLQLALSVPPLICVAYFWLVPESVRWLLARNRREQAGVIIRR 317
            :|||   .||:|..|.:  |  .|:.|.||..|.:  .|.|..||:..:|:|:.|.::|..::..
Zfish   247 FAVGIMVVALVGYLVRV--WWIYQIILTLSTSPFL--LYCWKFPETPFYLMAKGRYKEAQELLDT 307

  Fly   318 AAKVNRRDISVELMASFKQQELDAETGQEDDVEGGLHVKKDDKIWLAVKEVARSHILMGRYAILL 382
            .|.:|  .:...|..|..|...| .|..:|:.: .:.|:|.    |::.::..|..:.||.|...
Zfish   308 MAYIN--GLPPTLKVSDLQDGCD-RTPLKDNKQ-AMEVEKR----LSMLDMFGSLKMAGRSATCW 364

  Fly   383 LIWAVNAIVYYGLSLNATSLSGNKYLNFALVCLVEIPGYSLAWLFLRRFGRRVALSGSLLLCSIT 447
            .||.:.::.||..||.:.:|.||:|:|..|...||:|.|.:....:.||||:...:.:|||..:.
Zfish   365 AIWFIGSLGYYVFSLGSVNLGGNQYINLFLAGAVEVPSYLIGCFAMDRFGRKKTCAPALLLGGVA 429

  Fly   448 CVASGFVTLAQGDWIPCQTGVESRHSWSCANWLVVTLFLVGKLGITSSFAVIYTFTAEMMPTVIR 512
            |:.  .:.:.|        .||.         |.:.|.:.||..|..:|.:||.:|.|:.||:||
Zfish   430 CML--IIVVPQ--------DVEV---------LAIVLSMTGKFAIAIAFGLIYLYTCELYPTIIR 475

  Fly   513 SGGVGVMSTFARFGAMLAPFVPLLASYYDPLPLLLFGTLSLVAGLLSLLLPETFNRKLPDTVEEA 577
            |..||..|...|.|:::|||...||..:..||.|:.|.|:.:.|:|::.||||....|..|:|||
Zfish   476 SLAVGSGSMMCRVGSVVAPFCVYLADIWIYLPQLIVGILAFIIGILTMFLPETLGEPLTSTLEEA 540

  Fly   578 IALG 581
            .|||
Zfish   541 EALG 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4630	NP_001260948.1	2A0119	23..573	CDD:273328	164/571 (29%)
slc22a16	NP_001020659.1	MFS_SLC22A16_CT2	115..526	CDD:340933	131/442 (30%)