DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4630 and oatx

DIOPT Version :9

Sequence 1:	NP_001260948.1	Gene:	CG4630 / 36458	FlyBaseID:	FBgn0033809	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	XP_017208528.1	Gene:	oatx / 555218	ZFINID:	ZDB-GENE-070115-1	Length:	567	Species:	Danio rerio

Alignment Length:	573	Identity:	172/573 - (30%)
Similarity:	280/573 - (48%)	Gaps:	60/573 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LDFDDILVEIGEFGRFQRRNYLLICLPVLFAAANSLSYVFTAGSPTYRCYVPECDKLVDAEYGAN 77
            :.|.|:|.|:|.|||||..:..|:.:|.|..|:.:|...||||.|.:.|.:|.....:: :....
Zfish     1 MGFADLLDEVGGFGRFQMIHVTLLSIPGLLMASQNLLNNFTAGVPEHHCRIPNVTTAMN-DSTTT 64

  Fly    78 WVSIAVPGSWSKRGHFTPSTCERFVANGDHLESSSDPWSAWPLDQCFAENFT-TETERC-NQFVY 140
            .:...:|...|    .|.|.|.|:.....||.:          |:....|.| .:||.| :.:.|
Zfish    65 LLRAFIPLDSS----LTLSKCSRYKDTQWHLIT----------DKLSHGNATELQTEGCADGWTY 115

  Fly   141 GSSE--RTIVQQWGLQCPENLWKLAFVGTIHFAGLVVGTALSGYLADRYGRKHIFLFCIVFMALT 203
            ..||  .:||.:|.|.|.....| ....||:..|::.|..:.|.|:||:|||.:.::....:||.
Zfish   116 DKSEFISSIVSEWDLVCTLRPLK-QMSQTIYMGGVLTGAIIFGGLSDRFGRKALLIWSYFQLALL 179

  Fly   204 GVAQALSWDYISFLFFALLNAVGTSGVYPLAFIIGVEMVGPRKREMSSIVLNYFYAVGEALL-GL 267
            |...||:..|:.:..|..|..:..|||...|..:.||.:..:.|.:...:.::|:..|:.:| |:
Zfish   180 GSFTALAPSYVVYCIFRFLTGMSVSGVILNAVSLKVEWIPTKTRTLVGTLSSFFFTFGQMVLAGV 244

  Fly   268 SVFLPDWRQLQLALSVPPLICVAYFWLVPESVRWLLARNRREQAGVIIRRAAKVNRRDISVELMA 332
            :..|.|||::|:|:.:|..|...|.|...||.|||:...|.|:|..::.|.||:|.:.   |:..
Zfish   245 AYSLRDWRKIQMAVCLPFFIFFMYSWWFSESARWLVLNGRSEEALKLLHRVAKINGKP---EMTE 306

  Fly   333 SFKQQELDAETGQEDDVEGGLHVKKD---DKIWLAVKEVARSHILMGRYAILLLIWAVNAIVYYG 394
            ....:||::            |::|:   .|....|.::.|:..:......|:::|...:..|||
Zfish   307 KITLEELES------------HMQKEVQSSKSIYTVFDLLRTPTMRKISMCLMVVWFSTSFAYYG 359

  Fly   395 LSLNATSLSGNKYLNFALVCLVEIPGYSLAWLFLRRFGRRVALSGSLLLCSITCVASGFVTLAQG 459
            |:::......|.||...:...|:.|...:|.|.|...|||:. .|:.||.|.:.:.:..
Zfish   360 LAMDLQKFGVNIYLMQVIFGAVDFPAKLVALLMLSFLGRRLT-QGACLLVSASIIFANI------ 417

  Fly   460 DWIPCQTGVESRHSWSCANWLVVTLFLVGKLGITS-SFAVIYTFTAEMMPTVIRSGGVGVMSTFA 523
             ::|....|..           ..|.::|| |.|| ||..:|.||.|:.|||||..|:|.:||.:
Zfish   418 -FVPEDMQVTR-----------TALAVLGK-GFTSASFTCVYLFTGELYPTVIRQTGMGFVSTMS 469

  Fly   524 RFGAMLAPFVPLLASYYDPLPLLLFGTLSLVAGLLSLLLPETFNRKLPDTVEE 576
            |.|:|.||.|.:|......||.:::|..:::|||::.|||||.|..||||:::
Zfish   470 RIGSMAAPAVLILDDILPALPSIVYGGSAVIAGLIAFLLPETLNIPLPDTIDD 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4630	NP_001260948.1	2A0119	23..573	CDD:273328	166/558 (30%)
CG4630	NP_001260948.1	MFS	158..533	CDD:119392	110/379 (29%)
oatx	XP_017208528.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	7.030