Protein Alignment CG4630 and SLC22A15

DIOPT Version :9

• Sequence 1: NP_001260948.1
• Gene: CG4630 / 36458
• FlyBaseID: FBgn0033809
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_060890.2
• Gene: SLC22A15 / 55356
• HGNCID: 20301
• Length: 547
• Species: Homo sapiens
• Alignment Length: 593
• Identity: 168/593 - (28%)
• Similarity: 262/593 - (44%)
• Gaps: 107/593 - (18%)

  Fly    13 LDFDDILVEIGEFGRFQRRNYLLICLPV---LFAAANSLSYVFTAGSPTYRCYVPECDKLVDAEY 74
            ::.::....:||.|.:|.  ||...|.|   |:.|..::.......:|:|...:.|
Human     1 MEVEEAFQAVGEMGIYQM--YLCFLLAVLLQLYVATEAILIALVGATPSYHWDLAE--------- 54

  Fly    75 GANWVSIAVPGSWSKRGHFTPSTCERFVANGDHLESSSDPWSAWPLDQCFAE-NFTTETERCNQF 138
                                      .:.|..|...|:..      ||.|.: ..|......::.
Human    55 --------------------------LLPNQSHGNQSAGE------DQAFGDWLLTANGSEIHKH 87

  Fly   139 VYGSSERT-IVQQWGLQCPENLWKLAFVGTIHFAGLVVGTALSGYLADRYGRKHIFLFCIVFMAL 202
            |:.||..| |..:|.| .....:|::...:..|:|:.||....|.|:||:|||.::|.......|
Human    88 VHFSSSFTSIASEWFL-IANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGFALDIL 151

  Fly   203 TGVAQALSWDYISFLFFALLNAVGTSGVYPLAFIIGVEMVGPRKREMSSIVLNYFYAVG---EAL 264
            ..:|...|..|..|.....|..:...|:..:||::..|.||.....::..:...|:|||   .||
Human   152 FAIANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLFFAVGIAQYAL 216

  Fly   265 LGLSVFLPDWRQLQLALSVPPLICVAYFWLVPESVRWLLARNRREQAGVIIRRAAKVNRRDISVE 329
            ||  .|:..||.|.:.:::...:.......:|||.|||.::.|..:|...:...||.||: :...
Human   217 LG--YFIRSWRTLAILVNLQGTVVFLLSLFIPESPRWLYSQGRLSEAEEALYLIAKRNRK-LKCT 278

  Fly   330 LMASFKQQELDAETGQEDDVEGGLHVKKDDKIWLAVKEVARSHILMGRYAILLLIWAVNAIVYYG 394
            ...:........|||                   :..::.|..:|:|...||:.||.|.::||||
Human   279 FSLTHPANRSCRETG-------------------SFLDLFRYRVLLGHTLILMFIWFVCSLVYYG 324

  Fly   395 LSLNATSLSGNKYLNFALVCLVEIPGYSLAWLFLRR--FGRRVALSGSLLLCSITCVASGFVTLA 457
            |:|:|..|.|:.|.|.||..|:|||.|.|....:.:  |||:..||..|.|..:.|:...|:...
Human   325 LTLSAGDLGGSIYANLALSGLIEIPSYPLCIYLINQKWFGRKRTLSAFLCLGGLACLIVMFLPEK 389

  Fly   458 QGDWIPCQTG---VESRHSWSCANWLVVTLFLVGKLGITSSFAVIYTFTAEMMPTVIRSGGVGVM 519
            :      .||   |.:.||          |.|:|||.|:::|.::|.:|:|:.|||||:.|:|..
Human   390 K------DTGVFAVVNSHS----------LSLLGKLTISAAFNIVYIYTSELYPTVIRNVGLGTC 438

  Fly   520 STFARFGAMLAPFVPLLASYYDPLPLLLFGTLSLVAGLLSLLLPETFNRKLPDTV---------- 574
            |.|:|.|.::|||:|.|......||.::||...|.:||||||||||.|..|.:|.
Human   439 SMFSRVGGIIAPFIPSLKYVQWSLPFIVFGATGLTSGLLSLLLPETLNSPLLETFSDLQVYSYRR 503

  Fly   575 --EEAIAL 580
              |||::|
Human   504 LGEEALSL 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4630	NP_001260948.1	2A0119	23..573	CDD:273328	163/562 (29%)
		MFS	158..533	CDD:119392	116/382 (30%)
SLC22A15	NP_060890.2	MFS	111..469	CDD:119392	121/395 (31%)
		MFS_1	111..450	CDD:284993	113/376 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	522..547

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.930