Protein Alignment CG4630 and SLC22A17

DIOPT Version :9

• Sequence 1: NP_001260948.1
• Gene: CG4630 / 36458
• FlyBaseID: FBgn0033809
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_065105.3
• Gene: SLC22A17 / 51310
• HGNCID: 23095
• Length: 649
• Species: Homo sapiens
• Alignment Length: 622
• Identity: 158/622 - (25%)
• Similarity: 243/622 - (39%)
• Gaps: 139/622 - (22%)

  Fly    13 LDFDDILVEIGEFGRFQRRNYLLICLPVLFAAANSLS-YVFTAGSPTYRCYVPECDKLVDAEYGA 76
            |.|:.:|.::|..|..|:....|.||||||.|....| .:||...|.: |:           |||
Human    78 LSFEALLAQVGALGGGQQLQLGLCCLPVLFVALGMASDPIFTLAPPLH-CH-----------YGA 130

  Fly    77 ------NW--------VSIA----VPGSWSKRGHFTPSTCERFV-ANGDHLESSSDPWSAWPLDQ 122
                  .|        ||:|    ...:.|:....|..:|..|. .:.:|.....| ::..|:
Human   131 FPPNASGWEQPPNASGVSVASAALAASAASRVATSTDPSCSGFAPPDFNHCLKDWD-YNGLPV-- 192

  Fly   123 CFAENFTTETERCNQFVYGSSERTIVQQWGLQCPENLWKLAFVGTIHFAGLVVGTALSGYLADRY 187
                 .||..               :.||.|.|... |::.....:...|...|....||.|||:
Human   193 -----LTTNA---------------IGQWDLVCDLG-WQVILEQILFILGFASGYLFLGYPADRF 236

  Fly   188 GRKHIFLFCIVFMALTGVAQALSWDYISFLFFALLNAVGTS-GVYPLAFIIG------------- 238
            ||:.|.|..:..:...||..|               |.|:| ||..|.|::|
Human   237 GRRGIVLLTLGLVGPCGVGGA---------------AAGSSTGVMALRFLLGFLLAGVDLGVYLM 286

  Fly   239 -VEMVGPRKREMSSIVLNYFYAVGEAL-LGLSVFLPDWRQLQLALSVPPLICVAYFW--LVPESV 299
             :|:..|.:|...::........|..| |||::...|||.||..::.|.::.:.|.|  |..||.
Human   287 RLELCDPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESA 351

  Fly   300 RWLLARNRREQAGVIIRRAAKVNRRDISVELMASFKQQELDAETGQE--DDVEGGLHVKKDDKIW 362
            |||:.:.:.|:|..::|..|:.||           ...::..|..||  .|:|....:.
Human   352 RWLIVKRQIEEAQSVLRILAERNR-----------PHGQMLGEEAQEALQDLENTCPLP------ 399

  Fly   363 LAVKEVARSHILMGR--YAILLLIWAVNAIVYYGLSLNATSLSGNKYLNFALVCLVEIPGYSLAW 425
             |....:.:.:|..|  :..||::...|.|.:...........|....:|.|..|:.....:||.
Human   400 -ATSSFSFASLLNYRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALAC 463

  Fly   426 LFL----RRFGRRVALSGSLLLCSITCVASGFVTLAQGD---------WIPCQTGVESRHSWSCA 477
            :||    .|||||..|   ||..::|.:|| .|.|...|         |  .|.|..:|.    .
Human   464 VFLGVTVDRFGRRGIL---LLSMTLTGIAS-LVLLGLWDCEHPIFPTVW--AQQGNPNRD----L 518

  Fly   478 NWLVVTLFLVGKLGITSSFAVIYTFT---AEMMPTVIRSGGVGVMSTFARFGAMLAPFVPLLASY 539
            |...:|.|.|  ||:.||.|.....|   ||::||.:|..|:|::......|.:..|...|...:
Human   519 NEAAITTFSV--LGLFSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGH 581

  Fly   540 YDPLPLLLFGTLSLVAGLLSLLLPETFNRKLPDTVEE 576
            ...|..::....:|:..|..:|||||..:.||:.:.:
Human   582 GAFLQHVVLAACALLCILSIMLLPETKRKLLPEVLRD 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4630	NP_001260948.1	2A0119	23..573	CDD:273328	155/607 (26%)
		MFS	158..533	CDD:119392	108/412 (26%)
SLC22A17	NP_065105.3	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010