Protein Alignment CG4630 and slc22a4

DIOPT Version :10

• Sequence 1: NP_001260948.1
• Gene: CG4630 / 36458
• FlyBaseID: FBgn0033809
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_989323.1
• Gene: slc22a4 / 394948
• XenbaseID: XB-GENE-5858686
• Length: 553
• Species: Xenopus tropicalis
• Alignment Length: 595
• Identity: 186/595 - (31%)
• Similarity: 297/595 - (49%)
• Gaps: 110/595 - (18%)

  Fly    14 DFDDILVEIGEFGRFQRRNYLLICLPVLFAAANSLSYVFTAGSPTYRCYVPECDKLVDAEYGANW 78
            |:|:....:||:||:|...:.|:...::....|.:|.:|.||.|.:||::||     .|...|.|
 Frog     3 DYDEATSFLGEWGRYQFMIFFLLSASIIPNGFNGMSVMFLAGIPEHRCHIPE-----SANLSAAW 62

  Fly    79 VSIAVPGSWSKRGHFTPSTCERF----VAN---------------GDHLESSSDPWSAWPLDQCF 124
            .:.::|     |.....|.|.|:    :.|               |...|...|.|
 Frog    63 RNASIP-----RQDGQDSQCRRYRLGTLTNYSALGLLPGRDVDVTGIEQEPCLDGW--------- 113

  Fly   125 AENFTTETERCNQFVYGSSERTIVQQWGLQCPENLWKLAFVGTIHFAGLVVGTALSGYLADRYGR 189
              |:       ::.:|.|   |||.:|.:.| ||.||.....::.|.|:::|:.:||.|:|.:||
 Frog   114 --NY-------SKSLYLS---TIVTEWDIVC-ENDWKGPLTTSLFFVGVLLGSFVSGQLSDSFGR 165

  Fly   190 KHIFLFCIVFMALTGVAQ--ALSWDYISFLFFALLNAVGTSGVYPLAFIIGVEMVGPRKREM-SS 251
            |.|....:.......:.|  :.||:..:.||  |:..:|....|..|||:|.|::|...|.: |:
 Frog   166 KKILFVTMAIQTGFSIVQVFSTSWEMFAILF--LIVGMGQISNYVAAFILGTEILGKSARIIFST 228

  Fly   252 IVLNYFYAVGEALLGL-SVFLPDWRQLQLALSVPPLICVAYFWLVPESVRWLLARNRREQAGVII 315
            :....|:|:|..:|.| :.|:.|||.|.|||::|.|.|:..:|::|||.:||:.:.|.|:|.|||
 Frog   229 LGTCIFFAIGYMMLPLFAYFIRDWRTLLLALTIPGLFCIPLWWIIPESPQWLICKGRLEEAEVII 293

  Fly   316 RRAAKVNRRDISVELMASFKQQELDAETGQEDDVEGGLHVKKDDKIWLAVKEVARSHILMGRY-- 378
            |:|||:||......:   ||..||      ||..|                ...||:.|:...
 Frog   294 RKAAKINRVPAPAVI---FKTTEL------EDIAE----------------RQKRSYTLLDLVKT 333

  Fly   379 -------AILLLIWAVNAIVYYGLSLNATSLSGNKYLNFALVCLVEIPGYSLAWLFLRRFGRRVA 436
                   .:.:.:|.:.:|.|:|:|||..:|.|:.:||..|:..:|:|....|||.||...||.:
 Frog   334 FNVRIITIMTVFLWLITSIGYFGISLNTPNLHGDPFLNCFLLAAIEVPSNIFAWLLLRYISRRYS 398

  Fly   437 LSGSLLLCSITCVASGFVTLAQGDWIPCQTGVESRHSWSCANWLVVTLFLVGKLGITSSFAVIYT 501
            :.|||||        |.|.|.....:|....:           |...|.:|||.|:|::|:::|.
 Frog   399 MCGSLLL--------GGVVLLLIQLVPLDLQI-----------LSTVLVMVGKFGVTAAFSMVYV 444

  Fly   502 FTAEMMPTVIRSGGVGVMSTFARFGAMLAPFVPLLASYYDPLPLLLFGTLSLVAGLLSLLLPETF 566
            :|||:.|||||:.|||:.|..:|.|::::|:...|.:|...||.:|.|:|::..|:|.|..||||
 Frog   445 YTAELYPTVIRNTGVGIGSVSSRIGSVISPYFVYLGAYNRLLPYILMGSLTVANGILVLFFPETF 509

  Fly   567 NRKLPDTVEE 576
            .:.||:|:|:
 Frog   510 GKPLPETIEQ 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4630	NP_001260948.1	2A0119	23..573	CDD:273328	182/581 (31%)
slc22a4	NP_989323.1	2A0119	12..516	CDD:273328	182/581 (31%)