Protein Alignment CG4630 and slc22a4

DIOPT Version :9

• Sequence 1: NP_001260948.1
• Gene: CG4630 / 36458
• FlyBaseID: FBgn0033809
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_957143.1
• Gene: slc22a4 / 393822
• ZFINID: ZDB-GENE-040426-1517
• Length: 553
• Species: Danio rerio
• Alignment Length: 592
• Identity: 178/592 - (30%)
• Similarity: 286/592 - (48%)
• Gaps: 100/592 - (16%)

  Fly    14 DFDDILVEIGEFGRFQRRNYLLICLPVLFAAANSLSYVFTAGSPTYRCYVPECDKLVDAEYGANW 78
            |:|||...:|.:|.||...:|.:.:.:|......|..||...:|.:.|.:||     .....:.|
Zfish     3 DYDDITSFLGTWGPFQLTVFLALAISILPNGFVGLYIVFVGDTPAHECLIPE-----QINISSVW 62

  Fly    79 VSIAVPGSWSKRGHFTPSTCERFVANGDHLESSSDPWSAWPLDQCFAENFT---------TETER 134
            ...|:| :..:.|....|:|.|:     .|::         |.|....|:|         .|||.
Zfish    63 RDAAIP-TQMQDGVLKRSSCSRY-----RLDT---------LRQLSMLNYTPNVEVNLSQIETEP 112

  Fly   135 C------NQFVYGSSERTIVQQWGLQCPENLWKLAFVGTIHFAGLVVGTALSGYLADRYGRKHIF 193
            |      :|..|.|   |||.:|.|.| |..:|.....:|:|.|::|||.|||.::|||||:.:.
Zfish   113 CVDGWSYSQEFYQS---TIVTEWDLVC-EREYKGPLTSSIYFCGVLVGTFLSGQMSDRYGRRPVL 173

  Fly   194 LFCIVFMALTGVAQAL--SWDYISFLFFALLNAVGTSGV--YPLAFIIGVEMVGPRKREM-SSIV 253
            ...:....:|.:.|..  ||:..|.::|    .||.||.  |.:|:::|.|::.|..|.: .|:.
Zfish   174 FTMMALQTITILIQMFSPSWEVFSAIYF----FVGFSGFSNYVVAYVLGSEILSPASRVLFGSLG 234

  Fly   254 LNYFYAVGEALLGLSV-FLPDWRQLQLALSVPPLICVAYFWLVPESVRWLLARNRREQAGVIIRR 317
            :.....:|:....|:. |:..||.|.|..::..|:....:|.:|||.||||::.|..:|..::||
Zfish   235 VFMGSGIGQMFFPLAAYFIRSWRWLVLTNALTGLLYFPLWWFIPESPRWLLSQGRTAEAEAVLRR 299

  Fly   318 AAKVNRRDISVELMASFKQQELDAETGQEDDVEGGLHVKKDDKIWLAVKEVARSHIL-------- 374
            ||:.||......:.:|.:.:|                        .|.|.:.:..||
Zfish   300 AAEKNRVTAPEVIFSSSEIEE------------------------AAKKRIQKHSILDILSNCNA 340

  Fly   375 MGRYAILLLIWAVNAIVYYGLSLNATSLSGNKYLNFALVCLVEIPGYSLAWLFLRRFGRRVALSG 439
            :....|..|:|.|..:.||.|.||.|:|.||.||||.|..:||:|.|.:|.|.||...||:..:.
Zfish   341 VSTILICSLLWMVITMSYYALILNTTNLHGNPYLNFFLSAVVEVPAYIIAALLLRFCSRRICQAS 405

  Fly   440 SLLLCSITCVASGFVTLAQGDWIPCQTGVESRHSWSCANWLVVTLFLVGKLGITSSFAVIYTFTA 504
            :|||      ....:.:.|  .||.:           ...|...|.::|||.:|::|.|:|..|:
Zfish   406 TLLL------GGALIFIIQ--LIPTE-----------LQGLATALEMLGKLCVTAAFCVVYAVTS 451

  Fly   505 EMMPTVIRSGGVGVMSTFARFGAMLAPFVPLLASYYDPLPLLLFGTLSLVAGLLSLLLPETFNRK 569
            |:.|||:|:..:|..|..||.|::::||:..|.:||..:|.::.|.|:|.:|::||||||:..:.
Zfish   452 ELFPTVVRNMAMGSCSMTARIGSIISPFIIYLGNYYRYIPYIVIGGLALFSGVMSLLLPESKGKV 516

  Fly   570 LPDTVEE 576
            ||:|:.:
Zfish   517 LPETIAQ 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4630	NP_001260948.1	2A0119	23..573	CDD:273328	173/578 (30%)
		MFS	158..533	CDD:119392	117/388 (30%)
slc22a4	NP_957143.1	2A0119	12..520	CDD:273328	173/578 (30%)
		MFS	144..510	CDD:119392	128/412 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.980