DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4630 and Balat

DIOPT Version :9

Sequence 1:	NP_001260948.1	Gene:	CG4630 / 36458	FlyBaseID:	FBgn0033809	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	NP_610823.1	Gene:	Balat / 36417	FlyBaseID:	FBgn0033778	Length:	604	Species:	Drosophila melanogaster

Alignment Length:	598	Identity:	181/598 - (30%)
Similarity:	294/598 - (49%)	Gaps:	87/598 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LDFDDILVEIGEFGRFQRRNYLLICLPVLFAAA----NSLSYVFTAGSPTYRCYVPECDKLVDAE 73
            :|||::|.|:|.||.:|:   ::||..:|.||.    ::.|.:|.|.:|.:.|.|||.:.... :
  Fly     1 MDFDEVLREVGSFGLYQK---VIICSVLLPAALPCAFHAYSQLFIAATPQHFCRVPELEPWTQ-D 61

  Fly    74 YGANWVSIAVPGSWSKRGHFTPSTCERFVANGD----HLESSSDPWSAWPLDQCFAENF------ 128
            |.....::::|.  ::.|.:  :.|..:..|..    :||....|    .|.:..||:.
  Fly    62 YVQLVKNLSIPR--NRNGAY--AECSMYSRNYTDIVRYLEYRPPP----DLLRQQAEDLLKLQPD 118

  Fly   129 TTETERC------NQFVYGSSERTIVQQWGLQCPEN-LWKLAFVGTIHFAGLVVGTALSGYLADR 186
            ||:...|      ::.:|.|   |:||:|.|.|..: |..||.|  :...|.::|..:.|||.|.
  Fly   119 TTQVVPCQHGWHYDKSIYSS---TVVQEWNLVCDRSFLVTLALV--VFGVGGLLGNYVFGYLVDL 178

  Fly   187 YGRKHIFLFCIVFMALTGVAQALSWDYISFLFFALLNAVGTSGVYPLAFIIGVEMVGPRKREMSS 251
            :||:..|...::...:...|.|.:|:|.::|....:..:....:....:::.:|:|||.:|...:
  Fly   179 WGRRPSFYAYLLLEIIACAASAFAWNYYTWLGLRFVVGLTVPAILASPYVLAIELVGPERRVFCT 243

  Fly   252 IVLNYFYAVGEALL-GLSVFLPDWRQLQLALSVPPLICVAYFWLVPESVRWLLARNRREQAGVII 315
            ||.|..|::|..:| |:...:.|||:|.||:|:|.|:..:.|:::|||.|||:|..:..:|..|:
  Fly   244 IVSNIAYSLGLVVLAGVIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAVGKTRRAIKIL 308

  Fly   316 RRAAKVN----RRDISVELMASFKQQEL----DAETGQEDDVEGGLHVKKDDKIWLAVKEVARSH 372
            :..|:||    .||....|     |::|    .|||            |........:.::.|..
  Fly   309 KVMARVNGVRVNRDFVERL-----QRKLVITRAAET------------KSSMTTHYGILDLFRGP 356

  Fly   373 ILMGRYAILLLIWAVNAIVYYGLSLNATSLSGNKYLNFALVCLVEIPGYSLAWLFLRRFGRRVAL 437
            .:..:..|:.|||..|..||.|||..|.:|.|::..||.|...||:|.|.|.|..|..||||..|
  Fly   357 NMRRKTLIITLIWFANTSVYVGLSYYAPALGGDEIWNFFLAGAVELPTYLLLWPGLSYFGRRWIL 421

  Fly   438 SGSLLLCSITCVASGFVTLAQGDWIPCQTGVESRHSWSCANWLVVTLFLVGKLGITSSFAVIYTF 502
            ..|:|:..:.|||    |....|                   :.:.|:.|||:||:|||.|:...
  Fly   422 FISMLVGGVACVA----TFLYPD-------------------ITLLLYCVGKMGISSSFVVLPLM 463

  Fly   503 TAEMMPTVIRSGGVGVMSTFARFGAMLAPFVPLLASYYDPLPLLLFGTLSLVAGLLSLLLPETFN 567
            .:|:.|||:|..|:...|..:..|.::.|.:..:......|||::.|.|.::.|..|||||||.|
  Fly   464 ASELYPTVVRGLGMSFSSVISMVGPIVIPMINHMGQQMLVLPLIVMGALLILGGFASLLLPETRN 528

  Fly   568 RKLPDTVEEAIAL 580
            |.||.|:||..|:
  Fly   529 RNLPQTLEEGEAV 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4630	NP_001260948.1	2A0119	23..573	CDD:273328	172/579 (30%)
CG4630	NP_001260948.1	MFS	158..533	CDD:119392	116/384 (30%)
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	133/440 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458525
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	1	0.900	-	-		E33208_3B9N9
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I1021
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	8	7.890