Protein Alignment CG4630 and Slc22a4

DIOPT Version :9

• Sequence 1: NP_001260948.1
• Gene: CG4630 / 36458
• FlyBaseID: FBgn0033809
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_062661.1
• Gene: Slc22a4 / 30805
• MGIID: 1353479
• Length: 553
• Species: Mus musculus
• Alignment Length: 588
• Identity: 178/588 - (30%)
• Similarity: 308/588 - (52%)
• Gaps: 92/588 - (15%)

  Fly    14 DFDDILVEIGEFGRFQRRNYLLICLPVLFAAANSLSYVFTAGSPTYRCYVPECDKLVDAEYGANW 78
            |:|:::..:||:|.|||..:.|:...::....|.:|.||.||:|.:||.||:...|     .::|
Mouse     3 DYDEVIAFLGEWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCLVPDTVNL-----SSSW 62

  Fly    79 VSIAVPGSWSKRGHFTPSTCERF----VANGDHLESSSDPWSAWPLDQCFAENFTTETERC---- 135
            .:.::|.. :|.|...|.:|.|:    :||...:  ..:|.....|:|       .|.|.|
Mouse    63 RNHSIPLE-TKDGRQVPQSCRRYRLATIANFSAM--GLEPGQDVDLEQ-------LEQESCLDGW 117

  Fly   136 --NQFVYGSSERTIVQQWGLQCPENLWKLAFVGTIHFAGLVVGTALSGYLADRYGRKHI------ 192
              ::.::.|   |||.:|.|.| |:.||.....::.|.|::.|:.:||.|:||:|||.:
Mouse   118 EYDKDIFLS---TIVTEWNLVC-EDDWKTPLTTSLFFVGVLCGSFVSGQLSDRFGRKKVLFATMA 178

  Fly   193 ----FLFCIVFMALTGVAQALSWDYISFLFFALLNAVGTSGVYPLAFIIGVEMVGPRKREM-SSI 252
                |.|..:|        :.:|:..:.||  .:..:|....|.:|||:|.|::....|.: |::
Mouse   179 VQTGFSFVQIF--------STNWEMFTVLF--AIVGMGQISNYVVAFILGTEILSKSVRIIFSTL 233

  Fly   253 VLNYFYAVGEALLGL-SVFLPDWRQLQLALSVPPLICVAYFWLVPESVRWLLARNRREQAGVIIR 316
            .:..|:|:|..:|.| :.|:.|||.|.|||::|.|.||..:|.:|||.|||:::.|..:|..||:
Mouse   234 GVCTFFAIGYMVLPLFAYFIRDWRMLLLALTLPGLFCVPLWWFIPESPRWLISQRRFAEAEQIIQ 298

  Fly   317 RAAKVNRRDISVELMASFKQQELDAETGQEDDVEGGLHVKKDDKIWLAVKEVARSHILMGRYAIL 381
            :|||:|.......:....:.|||::              .|..|:  .:.::.|:..:.....:.
Mouse   299 KAAKMNSIVAPAGIFDPLELQELNS--------------LKQQKV--IILDLFRTRNIATITVMA 347

  Fly   382 LLIWAVNAIVYYGLSLNATSLSGNKYLNFALVCLVEIPGYSLAWLFLRRFGRRVALSGSLLLCSI 446
            :::|.:.::.|:.||||..:|.|:.|||..|..|:|:|.|..|||.||...||..::|.|..
Mouse   348 VMLWMLTSVGYFALSLNVPNLHGDVYLNCFLSGLIEVPAYFTAWLLLRTLPRRYIIAGVLFW--- 409

  Fly   447 TCVASGFVTLAQ---GDWIPCQTGVESRHSWSCANWLVVTLFLVGKLGITSSFAVIYTFTAEMMP 508
               ..|.:.|.|   .|:                |::.:.|.::||.||||:|:::|.||||:.|
Mouse   410 ---GGGVLLLIQVVPEDY----------------NFVSIGLVMLGKFGITSAFSMLYVFTAELYP 455

  Fly   509 TVIRSGGVGVMSTFARFGAMLAPFVPLLASYYDPLPLLLFGTLSLVAGLLSLLLPETFNRKLPDT 573
            |::|:..||:.|..:|.|:::||:...|.:|...||.:|.|:|:::.|:::|..||:|...||:.
Mouse   456 TLVRNMAVGITSMASRVGSIIAPYFVYLGAYNRLLPYILMGSLTVLIGIITLFFPESFGVTLPEN 520

  Fly   574 VEE 576
            :|:
Mouse   521 LEQ 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4630	NP_001260948.1	2A0119	23..573	CDD:273328	175/574 (30%)
		MFS	158..533	CDD:119392	119/389 (31%)
Slc22a4	NP_062661.1	2A0119	12..519	CDD:273328	174/573 (30%)
		MFS	123..510	CDD:119392	136/438 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9N9
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.880