DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4630 and SPBC8E4.01c

DIOPT Version :9

Sequence 1:	NP_001260948.1	Gene:	CG4630 / 36458	FlyBaseID:	FBgn0033809	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	NP_596846.2	Gene:	SPBC8E4.01c / 2541258	PomBaseID:	SPBC8E4.01c	Length:	572	Species:	Schizosaccharomyces pombe

Alignment Length:	509	Identity:	111/509 - (21%)
Similarity:	177/509 - (34%)	Gaps:	158/509 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   172 GLVVGTALSGYLADRYGRKHIF---LFCIVFMALTGVAQALS---------WDYISFLFFALLNA 224
            |.:.|..|.|::.|.:|||.::   :..::...:..:|...|         |.:.    :..|..
pombe   105 GNIFGQLLFGFMGDFFGRKFVYGKEMVIVIIATVLVIAMPKSIHSPLSKMMWVFC----WRWLLG 165

  Fly   225 VGTSGVYPLAFIIGVEMVGPRKREMSSIVLNYFYAVGEALLGLSVFL------------------ 271
            ||..|.||::..|..|....::|.....::..|...| .|.|..|.:
pombe   166 VGIGGDYPMSAAITSERSKIKRRGTLISLIFAFQGFG-TLAGAIVTIILLGCFEHPLNREGHYHK 229

  Fly   272 --PDWRQLQLALSVPPLICVAYFWLVPESVRWLLARNRREQAGVIIRRA------AKVNRRDIS- 327
              ..|| ||..|::.|.|.|    |:|   |.::..::..:....:..|      |..|..|..
pombe   230 LEGVWR-LQFGLALVPAIGV----LIP---RLIMKESKSYENSKALNSAEGKDPKAFFNTDDEDN 286

  Fly   328 ------------VELMASFKQQELDAETGQEDDVEGGLHVKKDDKIWLAVKEVARS-----HILM 375
                        ||....:..| .||...:.|::|         |.:.||.....|     :...
pombe   287 MKKSSSHGDSEVVEASDRYANQ-ADAADAEVDNIE---------KQFAAVTTPENSSGFITYFRQ 341

  Fly   376 GRYAILLL----IWAVNAIVYYGLSLNAT--------SLSGNKYL--------NFALVCLVEIPG 420
            .|:...||    .|.:..|.:||::||.:        |...|:|.        |..:.....:||
pombe   342 WRHFKHLLGTSVCWFLLDIAFYGVNLNQSVILKNIGFSTGTNEYRTLMKNAIGNLIIAVAGYVPG 406

  Fly   421 YSLAWLFLRRFGRR-VALSGSLLLCSITCVASG--FVTLAQGDWIPCQTGVESRHSWSCANWLVV 482
            |......:...||: :.|.|        .|.:|  |..|| |.|....||    ..::|  :::.
pombe   407 YWFNVFLVEILGRKWIQLQG--------FVITGLMFAILA-GRWNEISTG----GRFAC--FVIA 456

  Fly   483 TLFLVGKLGITSSF---AVIYTFTAEMMPTVIRSGGVGVMSTFARFGAMLAPFVPLLASYYDPLP 544
            .||        |:|   :..:.:.||:.|..:|....||.:...:.||:||.
pombe   457 QLF--------SNFGPNSTTFIYPAEVFPARVRGTAHGVSAALGKCGAILAS------------- 500

  Fly   545 LLLFGTLSLVAG----------------LLSLLLPETFNRKLPDTVEEAIALGK 582
             |||..|:.|.|                |.:||||||..|...:.....:..||
pombe   501 -LLFNFLTGVIGYGNVMWIFCGCMWGGILFTLLLPETKGRDADEIDRLELFYGK 553

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4630	NP_001260948.1	2A0119	23..573	CDD:273328	109/498 (22%)
CG4630	NP_001260948.1	MFS	158..533	CDD:119392	95/442 (21%)
SPBC8E4.01c	NP_596846.2	2A0109	27..547	CDD:129965	109/501 (22%)
SPBC8E4.01c	NP_596846.2	MFS	48..534	CDD:119392	104/488 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
TreeFam	0	0.000	Not matched by this tool.
	1	1.000