Protein Alignment CG4630 and Slc22a15

DIOPT Version :9

• Sequence 1: NP_001260948.1
• Gene: CG4630 / 36458
• FlyBaseID: FBgn0033809
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_001034460.2
• Gene: Slc22a15 / 242126
• MGIID: 3607704
• Length: 544
• Species: Mus musculus
• Alignment Length: 593
• Identity: 170/593 - (28%)
• Similarity: 263/593 - (44%)
• Gaps: 107/593 - (18%)

  Fly    13 LDFDDILVEIGEFGRFQRRNYLLICLPV---LFAAANSLSYVFTAGSPTYRCYVPECDKLVDAEY 74
            ::.::....:||.|.:|.  ||...|.|   |:.|..::.......:|.|  :....|.|.:..:
Mouse     1 MEVEEAFQAVGEMGLYQM--YLCFLLAVLLQLYVATEAILIALIGATPAY--HWDMADLLPNQSH 61

  Fly    75 GANWVSIAVP-GSWSKRGHFTPSTCERFVANGDHLESSSDPWSAWPLDQCFAENFTTETERCNQF 138
            ....:..... |.|            ...|||..:.....          |:.:||
Mouse    62 SNQTLGKGQAFGDW------------LLTANGSEIHKHVH----------FSNSFT--------- 95

  Fly   139 VYGSSERTIVQQWGLQCPENLWKLAFVGTIHFAGLVVGTALSGYLADRYGRKHIFLFCIVFMALT 203
                   :|..:|.| .....:|::...:..|:|:.||....|.|:||:||:.::|.......|.
Mouse    96 -------SIASEWFL-IANRSYKVSAASSSFFSGVFVGVISFGQLSDRFGRRKVYLTGFALDILF 152

  Fly   204 GVAQALSWDYISFLFFALLNAVGTSGVYPLAFIIGVEMVGPRKREMSSIVLNYFYAVG---EALL 265
            .||...|..|..|.....|..:...|:..:||::..|.||.....::..:...|:|||   .|||
Mouse   153 AVANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLFFAVGIAQYALL 217

  Fly   266 GLSVFLPDWRQLQLALSVPPLICVAYFWLVPESVRWLLARNRREQAGVIIRRAAKVNRRDISVEL 330
            |  .|:..||.|.:.:::...:.......:|||.|||.::.|..:|...:...||.||:     |
Mouse   218 G--YFIRSWRTLAVLVNLQGTLVFLLSLFIPESPRWLYSQGRLSEAEEALYFIAKRNRK-----L 275

  Fly   331 MASFKQQELDAETGQEDDVEGGLHVKKDDKIWLAVKEVARSHILMGRYAILLLIWAVNAIVYYGL 395
            ..:|   .|.....:.....|            :..::.|..||:|...||:.||.|.::|||||
Mouse   276 KCTF---SLTHPANRSYRATG------------SFLDLFRYRILLGHTLILMFIWFVCSLVYYGL 325

  Fly   396 SLNATSLSGNKYLNFALVCLVEIPGYSLAWLFL---RRFGRRVALSGSLLLCSITCVASGFVTLA 457
            :|:|..|.|:.|.|.||..|:|||.|.|. ::|   |.|||:..|:..|.|..:.|:...|:...
Mouse   326 TLSAGDLGGSIYANLALSGLIEIPSYPLC-IYLINQRWFGRKRTLAAFLCLGGLACLIVMFLPEK 389

  Fly   458 QGDWIPCQTG---VESRHSWSCANWLVVTLFLVGKLGITSSFAVIYTFTAEMMPTVIRSGGVGVM 519
            :      .||   |.:.||          |.|:|||.|:::|.::|.:|:|:.|||||:.|:|..
Mouse   390 K------DTGVFAVVNSHS----------LSLLGKLTISAAFNIVYIYTSELYPTVIRNVGLGAC 438

  Fly   520 STFARFGAMLAPFVPLLASYYDPLPLLLFGTLSLVAGLLSLLLPETFNRKLPDTV---------- 574
            |.|:|.|.::|||||.|......||.::||...|.:||||||||||.|..|.:|.
Mouse   439 SMFSRVGGIIAPFVPSLKEVQWSLPFIVFGATGLTSGLLSLLLPETLNSPLLETFSDLQMYSYRR 503

  Fly   575 --EEAIAL 580
              |||::|
Mouse   504 LGEEALSL 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4630	NP_001260948.1	2A0119	23..573	CDD:273328	165/562 (29%)
		MFS	158..533	CDD:119392	119/383 (31%)
Slc22a15	NP_001034460.2	MFS	121..469	CDD:119392	124/386 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	513..544

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920