Protein Alignment CG4630 and Slc22a8

DIOPT Version :10

• Sequence 1: NP_001260948.1
• Gene: CG4630 / 36458
• FlyBaseID: FBgn0033809
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_112471.3
• Gene: Slc22a8 / 19879
• MGIID: 1336187
• Length: 537
• Species: Mus musculus
• Alignment Length: 571
• Identity: 167/571 - (29%)
• Similarity: 265/571 - (46%)
• Gaps: 72/571 - (12%)

  Fly    13 LDFDDILVEIGEFGRFQRRNYLLICLPVLFAAANSLSYVFTAGSPTYRCYVPECDKLVDAEYGAN 77
            :.|.:||..:|..|.||..:..|:.||:|..|.::|..:|||.:|.:.|..|....|      ..
Mouse     1 MTFSEILDRVGSMGPFQYLHVTLLALPILGIANHNLLQIFTATTPDHHCRPPPNASL------EP 59

  Fly    78 WVSIAVPGSWSKRGHFTPSTCERFVANGDHLESSSDPWSAWPLDQCFAENFTT-ETERC-NQFVY 140
            ||....|..       .|..|.|||    ||.::|.|            |.|. .||.| :.::|
Mouse    60 WVLPLGPNG-------KPEKCLRFV----HLPNASLP------------NDTQGATEPCLDGWIY 101

  Fly   141 GSSERTIVQQWGLQCPENLWKLAFVGTIHFAGLVVGTALSGYLADRYGRKHIFLFCIVFMALTGV 205
            .|:..|||.:|.|.|..|..| ....::..||::||..:.|.|:||:|||.|..:..:.:|.:|.
Mouse   102 NSTRDTIVTEWDLVCGSNKLK-EMAQSVFMAGILVGGPVFGELSDRFGRKPILTWSYLLLAASGS 165

  Fly   206 AQALSWDYISFLFFALLNAVGTSGVYPLAFIIGVEMVGPRKREMSSIVLNYFYAVGEALL-GLSV 269
            :.|.|.....::.|..|.....||:.....|:.||.|....|.:||..:.|.|.:|:.:| ||:.
Mouse   166 SAAFSPSLTVYMIFRFLCGCSISGISLSTIILNVEWVPTSTRAISSTTIGYCYTIGQFILPGLAY 230

  Fly   270 FLPDWRQLQLALSVPPLICVAYFWLVPESVRWLLARNRREQAGVIIRRAAKVNRRDISVELMASF 334
            .:|.||.|||::|....|.....|.||||:|||:...:..:|...::|.|..|.:
Mouse   231 AVPQWRWLQLSVSAAFFIFSLLSWWVPESIRWLVLSGKFSKALKTLQRVATFNGK---------- 285

  Fly   335 KQQELDAETGQEDDVEG-GLHVKKD---DKIWLAVKEVARSHILMGRYAILLLIWAVNAIVYYGL 395
                  .|.|::..||. ..:::||   .|:...:.::.|..||......|.|.|......||.|
Mouse   286 ------KEEGEKLTVEELKFNLQKDITSAKVKYGLSDLFRVSILRRVTFCLSLAWFATGFAYYSL 344

  Fly   396 SLNATSLSGNKYLNFALVCLVEIPGYSLAWLFLRRFGRRVALSGSLLLCSITCVASGFVTLAQGD 460
            ::.......|.|:...:...|:||...:..|.:...|||:.....|:|..:..:|..||:
Mouse   345 AMGVEEFGVNIYILQIIFGGVDIPAKFITILSISYLGRRITQGFLLILAGVAILALIFVS----- 404

  Fly   461 WIPCQTGVESRHSWSCANWLVVTLFLVGKLGITSSFAVIYTFTAEMMPTVIRSGGVGVMSTFARF 525
                          |....|...|.:.||..::.||:.::.:|:|:.|||:|..|:|:.:.:||.
Mouse   405 --------------SEMQLLRTALAVFGKGCLSGSFSCLFLYTSELYPTVLRQTGMGISNIWARV 455

  Fly   526 GAMLAPFVPLLASYYDPLPLLLFGTLSLVAGLLSLLLPETFNRKLPDTVEE 576
            |:|:||.|.:.......:|.::|||::|:.|..:..|.||.||.||:|:|:
Mouse   456 GSMIAPLVKITGELQPFIPNVIFGTMTLLGGSAAFFLLETLNRPLPETIED 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4630	NP_001260948.1	2A0119	23..573	CDD:273328	162/556 (29%)
Slc22a8	NP_112471.3	2A0119	11..503	CDD:273328	162/556 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	513..537