Protein Alignment CG4630 and K05F1.6

DIOPT Version :9

• Sequence 1: NP_001260948.1
• Gene: CG4630 / 36458
• FlyBaseID: FBgn0033809
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_001342018.1
• Gene: K05F1.6 / 173977
• WormBaseID: WBGene00019408
• Length: 858
• Species: Caenorhabditis elegans
• Alignment Length: 619
• Identity: 158/619 - (25%)
• Similarity: 275/619 - (44%)
• Gaps: 98/619 - (15%)

  Fly     7 GAASAVLDFDDILVEIGEFGRFQRRNYLLICLPVLFAAANSLSYVFTAGSPTYRCYVPECDKLVD 71
            |..:..:||:.||..||....:|...|:||.|..:..|..:|:.|:....|.::|.||..:...|
 Worm   194 GKPTDPIDFEGILNIIGGCRWWQIWIYVLIALQQIPHAMFNLNVVYMMYDPEFQCMVPGFNDTND 258

  Fly    72 AEYGAN----W-------VSIAVPGSWSKRGHFTPSTCERFVANGDH--------LESS-SDPW- 115
            ....::    |       :|...|.: :..|.:...:|..:..:.:.        ||:: |:.|
 Worm   259 TTISSHGPYLWGVDDIKNISFVFPNA-NSDGAYQRDSCYFYERSEERYRQLRRMPLETAMSEAWK 322

  Fly   116 SAWPLDQCFAENFTTETERCNQFVYGSSERTIVQQWGLQCPENLWKLAFVGTIHF---AGLVVGT 177
            ...|..:|.|.:|..:.          ...|||..:.|.|.....|    |..|.   .|.::|.
 Worm   323 DVAPKKKCQAYHFEKDV----------MVETIVTDFNLVCDSWFAK----GHAHMFYSIGYLLGC 373

  Fly   178 ALSGYLADRYGRKHIFLFCIVFMALTGVAQALSWDYISFLFFALLNAVGTSGVYPLAFIIGVEMV 242
            .|.|..:|:.|||...:...:..::.||....:..|..||...||:|:........|:.:.:|:.
 Worm   374 VLGGIASDKIGRKPTIIGFGILSSMLGVFLPFNDYYPMFLLIRLLSAICNEAADLAAYTLCMEIT 438

  Fly   243 GPRKREMSSIVLNYFYAVGEALLGLSVFL-PDWRQLQLALSVPPLICVAYFWLVPESVRWLLARN 306
            |.:.|.|...:|...:|:|.|||.|..:| ..|:.:|:..:....:.:.:...:|||.|||:.:|
 Worm   439 GTKYRAMVGSMLQAPWALGYALLALIAYLTKSWKTIQVIAAGLHFMSIIFICSIPESPRWLMVQN 503

  Fly   307 RREQAGVIIRRAAKVNRRDISVELMASFKQQELDAETGQEDDVEGGLHVKKDDKI----WLAVKE 367
            |..:|..:||:|.:  .......:..:.|...|.::.......|..|:.|...||    ...:||
 Worm   504 RVSEAEEVIRKACR--EPPFPFNMCTTSKCGNLPSDLELVSHRERKLNKKNGGKIGFLDLFTMKE 566

  Fly   368 VARSHILMGRYAIL--LLIWAVNAIVYYGLSL--------NATSLSGNKYLNFALVCLVEIPG-Y 421
            :        ||..:  .:::...|:|||||.:        ..|..:|..:||..:...:|||. :
 Worm   567 L--------RYRTISVCIVFMATALVYYGLVMALSDQSAPGRTLFTGYFHLNNGIAGAIEIPTLF 623

  Fly   422 SLAWLFLRRFGRRVAL------SGSLLLCSITCVASGFVTLAQGDWIPCQTGVESRHSWSCANWL 480
            :..|:.  :.||:.||      ||..::.::..:.||...||
 Worm   624 ACVWMM--QLGRKKALMLTLITSGLFIIVAMLSMVSGHYMLA----------------------- 663

  Fly   481 VVTLFLVGKLGITSSFAVIYTFTAEMMPTVIRSGGVGVMSTFARFGAMLAPFVPLLASYYDPL-P 544
             :.....||:.:..:|.::|.||:|:.|||:|:..|||.|..||||:.|:.::.||::...|: |
 Worm   664 -LAFMYFGKIAVQGAFNILYIFTSELYPTVVRNTAVGVTSMVARFGSGLSSYIALLSNISLPIVP 727

  Fly   545 LLLFGTLSLVAGLLSLLLPETFNRKLPDTVEEAI 578
            :::|...||.||:|..:||||..:.||:|:::||
 Worm   728 MIIFAVFSLFAGMLVFVLPETSEKPLPETLDDAI 761

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4630	NP_001260948.1	2A0119	23..573	CDD:273328	149/596 (25%)
		MFS	158..533	CDD:119392	101/399 (25%)
K05F1.6	NP_001342018.1	MFS_SLC22	333..746	CDD:340875	117/462 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163102
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.850