DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4630 and Ust5r

DIOPT Version :9

Sequence 1:	NP_001260948.1	Gene:	CG4630 / 36458	FlyBaseID:	FBgn0033809	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	NP_599207.2	Gene:	Ust5r / 171398	RGDID:	620985	Length:	552	Species:	Rattus norvegicus

Alignment Length:	599	Identity:	140/599 - (23%)
Similarity:	256/599 - (42%)	Gaps:	109/599 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 FDDILVEIGEFGRFQRRNYLLICLPVLFAAANSLSYVFTAGSPTYRCYVPECDKLVDAEYGA--- 76
            |.::|.::|..||||......:.|..:....:|....|||..|::||:||..|.:..::..:
  Rat     3 FQELLNQVGSLGRFQILQMAFVFLINVSVVPHSTIENFTAAIPSHRCWVPILDNVTVSDNHSRIL 67

  Fly    77 ---NWVSIAVPGSWSKRGHFTPSTCERFVANGDHLESSSDPWSAWPLDQCFAENFTTETERC-NQ 137
               ..:.|::|    ...|.....|.||         :...|....|:..|:.....:||.| :.
  Rat    68 NQDKLLKISIP----LDSHLRLDKCRRF---------AQPQWHLLDLNDTFSSVTEADTEPCVDG 119

  Fly   138 FVYGSS--ERTIVQQWGLQCP----ENLWKLAFVGTIHFAGLVVGTALSGYLADRYGRKHIFLFC 196
            :||..|  ..|.|.:|.|.|.    .::.|.:|:     .|..:|..::|.|:||:|||.:....
  Rat   120 WVYDRSNFHSTTVTEWDLVCESQVLNSVTKFSFM-----IGAFIGGIVNGPLSDRFGRKFVLKCA 179

  Fly   197 IVFMALTGVAQALSWDYISFLFFALLNAVGTSGVYPLAFIIGVEMVGPRKREMSSIVLNYFYAVG 261
            ::.||:|......:.::..:.....|..:....:...:.::..|....:...|.|::.....:.|
  Rat   180 LLQMAITETCVGFASNFFIYCSLRFLAGMTFEPILVNSNLLMFEWTSHKFLAMMSVIAPCAGSFG 244

  Fly   262 EALL-GLSVFLPDWRQLQLALSVPPLICVAYFWLV-----PESVRWLLARNRREQAGVIIRRAAK 320
            ..:| ||:....:|..||||:|||     .:|:|:     .||.|||:..|:.::....:|:.|.
  Rat   245 SMILAGLAFQFQNWHHLQLAMSVP-----IFFFLILTRWLSESARWLIVTNKPQKGLKELRKVAH 304

  Fly   321 VNRR-----DISVELMASFKQQELDAETGQEDDVEGGLHVKKDDKIWLAVKEVARSHILMGRYAI 380
            :|..     ::::|::.:..::||:|...:.                 :.:::..:.||..|...
  Rat   305 MNGMKNSGDNLTMEVVRTSMKRELEAAKARP-----------------SPRDLFHTPILRKRICA 352

  Fly   381 LLLIWAVNAIVYYGLSLNATSLSGNKYLNFALVCLVEIPGYSLAWLF-------LRRFGRRV--- 435
            :..:..:..:..:|:||:...||.|       :.|::....:.:.||       ..|.|||:
  Rat   353 MSFMRILFMLSIFGMSLHLQHLSSN-------IMLLQFVVSASSLLFSVIGPYVFNRMGRRITQM 410

  Fly   436 ---ALSGSLLLCSITCVASGFVTLAQGDWIPCQTGVESRHSWSCANWLVVTLFLVGKLGITSSFA 497
               .|.|   :|.:|.|           ::|.:..:           |.:|:..:.......||.
  Rat   411 VVMTLRG---ICILTAV-----------FVPQEMQI-----------LRITVVTLAGAFSALSFG 450

  Fly   498 VIYTFTAEMMPTVIRSGGVGVMSTFARFGAMLAPFVPLLASYYDPLPLLLFGTLSLVAGLLSLLL 562
            |....|.|::||.:|:..:||:..|...|..|||...:||||...||.:.:|..|::.|....||
  Rat   451 VNRLHTNELLPTTLRATAIGVIGMFGNSGFFLAPLFMILASYSPNLPWIFYGGFSILNGFTVFLL 515

  Fly   563 PETFNRKLPDTVEE 576
            |||.|:.|||.:.:
  Rat   516 PETKNQPLPDCIHD 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4630	NP_001260948.1	2A0119	23..573	CDD:273328	137/586 (23%)
CG4630	NP_001260948.1	MFS	158..533	CDD:119392	84/398 (21%)
Ust5r	NP_599207.2	MFS_OAT	109..516	CDD:340932	105/465 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347319
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.940