DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4630 and UST4r

DIOPT Version :9

Sequence 1:	NP_001260948.1	Gene:	CG4630 / 36458	FlyBaseID:	FBgn0033809	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	NP_599206.2	Gene:	UST4r / 171397	RGDID:	620976	Length:	552	Species:	Rattus norvegicus

Alignment Length:	598	Identity:	145/598 - (24%)
Similarity:	260/598 - (43%)	Gaps:	107/598 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 FDDILVEIGEFGRFQRRNYLLICLPVLFAAANSLSYVFTAGSPTYRCYVPECDKLVDAEYGA--- 76
            |.::|.::|..||||....:.:....:....:.:...|||..|::||:||..|.:..::..:
  Rat     3 FQELLNQVGGLGRFQILQMVFVVFTSVIVVPHIIIENFTAAIPSHRCWVPILDNVTVSDNDSRIL 67

  Fly    77 ---NWVSIAVPGSWSKRGHFTPSTCERFVANGDHLESSSDPWSAWPLDQCFAENFTTETERC-NQ 137
               ..:.|::|    ...|.....|.||         :...|....|:..|:.....:||.| :.
  Rat    68 NQDKLLKISIP----LDSHLRLDKCRRF---------AQPQWHLLDLNDTFSSITEPDTEPCVDG 119

  Fly   138 FVYGSS--ERTIVQQWGLQCP----ENLWKLAFVGTIHFAGLVVGTALSGYLADRYGRKHIFLFC 196
            :||..|  ..|.|.:|.|.|.    .::.||:|:     .|..:|..::|.|:||:|||.|..:.
  Rat   120 WVYDRSNFHSTTVTEWNLVCESQALNSVTKLSFM-----IGAFIGGIVNGLLSDRFGRKFILKYA 179

  Fly   197 IVFMALT----GVAQALSWDYISFLFFALLNAVGTSGVYPLAFIIGV---EMVGPRKREMSSIVL 254
            ::.||:|    |.|..|      |::.:|....|.| :.|:...|.:   |...|:...|.:::.
  Rat   180 LLQMAITETCAGFAPNL------FIYCSLRFLAGMS-LEPITVNINLLMFEWTSPKFLTMVTVLG 237

  Fly   255 NYFYAVGEALL-GLSVFLPDWRQLQLALSVPPLICVAYFWLV-----PESVRWLLARNRREQAGV 313
            :...:.|..:| ||:....:|..||||:|||     .:|:|:     .||.|||:..|:.::...
  Rat   238 SCAGSFGGMILAGLAFQFQNWHHLQLAMSVP-----IFFFLILTRWLSESARWLIVINKPQKGLK 297

  Fly   314 IIRRAAKVNRR-----DISVELMASFKQQELDAETGQEDDVEGGLHVKKDDKIWLAVKEVARSHI 373
            .:::.|.:|..     :|::|::.:..::||:|.                 |:..:.:::..:.|
  Rat   298 ELKKVAHINGMKKSGDNITMEVVRTSMKKELEAA-----------------KMRPSPRDLFHTPI 345

  Fly   374 LMGRYAILLLIWAVNAIVYYGLSLNATSLSGNKYLNFALVCLVEIPGYSLAWLFLRRFGRRVALS 438
            |..:..||..|..:..:...|::::...||.|..|...|:.:..|....:....|...|||:...
  Rat   346 LRKQIYILSFIRLLFILSGVGVAIHLQHLSNNIELLQILISVSSILFSVIGHFVLNHIGRRITQM 410

  Fly   439 GSLLLCSITCVASGFV-----TLAQGDWIPCQTGVESRHSWSCANWLVVTLFLVGKLGITSSFAV 498
            ..:.|..|:.:.:.|.     ||.                      .::.:...|...:  |:|.
  Rat   411 VIMFLRGISILTAIFAPQEMETLR----------------------FIMAMMAEGLAAL--SYAA 451

  Fly   499 IYTFTAEMMPTVIRSGGVGVMSTFARFGAMLAPFVPLLASYYDPLPLLLFGTLSLVAGLLSLLLP 563
            ......|::||.:|:...||:..|...|..|||...:||||...||.:.:|..::::|.:.||||
  Rat   452 NSLHANELLPTTLRATARGVIGMFGNIGFFLAPLCMMLASYSPNLPWIFYGGFAILSGFIVLLLP 516

  Fly   564 ETFNRKLPDTVEE 576
            ||.|..|||...:
  Rat   517 ETKNNPLPDCTHD 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4630	NP_001260948.1	2A0119	23..573	CDD:273328	142/585 (24%)
CG4630	NP_001260948.1	MFS	158..533	CDD:119392	91/397 (23%)
UST4r	NP_599206.2	MFS_OAT	109..516	CDD:340932	112/464 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347322
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.940