Protein Alignment CG4630 and SLC22A31

DIOPT Version :9

• Sequence 1: NP_001260948.1
• Gene: CG4630 / 36458
• FlyBaseID: FBgn0033809
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_001371692.1
• Gene: SLC22A31 / 146429
• HGNCID: 27091
• Length: 446
• Species: Homo sapiens
• Alignment Length: 442
• Identity: 116/442 - (26%)
• Similarity: 195/442 - (44%)
• Gaps: 51/442 - (11%)

  Fly   149 QQWGLQCPENLWKLAFVGTIHFAGLVVGTALSGYLADRYGRKHIFLFCIVFMALTGVAQALSWDY 213
            |.|.|.|.:. ||:......|..|.::|..:.|...||:||:.:|:..:|.....|.::||:..:
Human     7 QNWNLVCGDG-WKVPLEQVSHLLGWLLGCVILGAGCDRFGRRAVFVASLVLTTGLGASEALAASF 70

  Fly   214 ISFLFFALLNAVGTSGVYPLAFIIGVEMVGPRKREMSSIVLNYFYAVGEALL-GLSVFLPDWRQL 277
            .:.|...||:....:|.....::..:|:..|..|...|:....|..||..|| ||:..:.|||.|
Human    71 PTLLVLRLLHGGTLAGALLALYLARLELCDPPHRLAFSMGAGLFSVVGTLLLPGLAALVQDWRLL 135

  Fly   278 Q-LALSVPPLICVAYFW----LVPESVRWLLARNRREQAGVIIRR---AAKVNRRDISVELMASF 334
            | |...:..|:.:  ||    |.|||..||||..:..:|..|:.|   |:.|...|.|:|..:..
Human   136 QGLGALMSGLLLL--FWGFPALFPESPCWLLATGQVARARKILWRFAEASGVGPGDSSLEENSLA 198

  Fly   335 KQQELDAETGQEDDVEGGLHVKKDDKIWLAVKEVARSHILMGRYAILLLIWAVNAIVYYGLSLNA 399
            .:..:.:....:......|.:.:....|       |:.:::|          .:::|..|:..:.
Human   199 TELTMLSARSPQPRYHSPLGLLRTRVTW-------RNGLILG----------FSSLVGGGIRASF 246

  Fly   400 TSLSGNKYLNFALVCLVE--IPGYSLAWLFLRR--FGRRVALSGSLLLCSITCVASGFVTLAQGD 460
            ......:...|.|...:|  :...:|.:|.|..  .|||..|   ||...:|.:|| .:.||...
Human   247 RRSLAPQVPTFYLPYFLEAGLEAAALVFLLLTADCCGRRPVL---LLGTMVTGLAS-LLLLAGAQ 307

  Fly   461 WIPCQTGVESRHSWSCANWLVVTLFLVGKLGITSSFAVIYTFTAEMMPTVIRSGGVGVMSTFARF 525
            ::|              .|.|:.|.::|.|...:..|:...|.||:.|||||..|:|::......
Human   308 YLP--------------GWTVLFLSVLGLLASRAVSALSSLFAAEVFPTVIRGAGLGLVLGAGFL 358

  Fly   526 GAMLAPFVPLLASYYDPLPLLLFGTLSLVAGLLSLLLPETFNRKLPDTVEEA 577
            |....|...|.......|..::|.:|:::|.|..|||||:.:|.||.::::|
Human   359 GQAAGPLDTLHGRQGFFLQQVVFASLAVLALLCVLLLPESRSRGLPQSLQDA 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4630	NP_001260948.1	2A0119	23..573	CDD:273328	115/436 (26%)
		MFS	158..533	CDD:119392	97/387 (25%)
SLC22A31	NP_001371692.1	MFS	9..383	CDD:421695	103/411 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010