Protein Alignment CG4630 and SLC22A9

DIOPT Version :9

• Sequence 1: NP_001260948.1
• Gene: CG4630 / 36458
• FlyBaseID: FBgn0033809
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_543142.2
• Gene: SLC22A9 / 114571
• HGNCID: 16261
• Length: 553
• Species: Homo sapiens
• Alignment Length: 605
• Identity: 167/605 - (27%)
• Similarity: 277/605 - (45%)
• Gaps: 120/605 - (19%)

  Fly    15 FDDILVEIGEFGRFQRRNYLLICLPVLFAAANSLSYV---FTAGSPTYRCYVP--ECDKLVDAEY 74
            |.|:|...|:..|||....:.:.   :||.|..|.::   |||..|.:||:|.  :.|.:.|.:.
Human     3 FQDLLGHAGDLWRFQILQTVFLS---IFAVATYLHFMLENFTAFIPGHRCWVHILDNDTVSDNDT 64

  Fly    75 GA----NWVSIAVPGSWSKRGHFTPSTCERFVANGDHLESSSDPWSAWPLDQCFAENFTTETERC 135
            ||    ..:.|::|...:.|    |..|.|||    |.:     |....|:..|......:.|.|
Human    65 GALSQDALLRISIPLDSNMR----PEKCRRFV----HPQ-----WQLLHLNGTFPNTSDADMEPC 116

  Fly   136 -NQFVYG--SSERTIVQQWGLQC-PENLWKLA-FVGTIHFAGLVVGTALSGYLADRYGRKHIFLF 195
             :.:||.  |...|||.:|.|.| .::|..:| ||   ..||::||..|.|:|:||:||:.:..:
Human   117 VDGWVYDRISFSSTIVTEWDLVCDSQSLTSVAKFV---FMAGMMVGGILGGHLSDRFGRRFVLRW 178

  Fly   196 CIVFMALTGVAQALSWDYISFLFFALLNAVGTSGVYPLAFIIGVEMVGPRKREMSSIVLNYFYAV 260
            |.:.:|:.|...||:   .:||.:..|..:  ||:..::.|....|:      ::....:.|.|:
Human   179 CYLQVAIVGTCAALA---PTFLIYCSLRFL--SGIAAMSLITNTIML------IAEWATHRFQAM 232

  Fly   261 G------------EALLGLSVFLPDWRQLQLALSVPPLICVAYF-------WLVPESVRWLLARN 306
            |            ..|.||:..:.||..|||.:|||      ||       ||: ||.|||:..|
Human   233 GITLGMCPSGIAFMTLAGLAFAIRDWHILQLVVSVP------YFVIFLTSSWLL-ESARWLIINN 290

  Fly   307 RREQAGVIIRRAA----KVNRRD-ISVELMASFKQQELDAETGQEDDVEGGLHVKKDDKIWLAVK 366
            :.|:....:|:||    ..|.|| :::|::.|..::||:|...::..:...||:..
Human   291 KPEEGLKELRKAAHRSGMKNARDTLTLEILKSTMKKELEAAQKKKPSLCEMLHMPN--------- 346

  Fly   367 EVARSHILMGRYAILLLIWAVNAIVYYGLSLNATSLSGNKYLNFALVCLVEIPGYSLAWLFLRRF 431
                   :..|.::|......|.:.|:||:|:...|..|.:|...|...|.:....:|...|:..
Human   347 -------ICKRISLLSFTRFANFMAYFGLNLHVQHLGNNVFLLQTLFGAVILLANCVAPWALKYM 404

  Fly   432 GRRVALSGSLLLCSITCVASGFV-----TLAQGDWIPCQTGVESRHSWSCANWLVVTLFLVGKLG 491
            .||.:....:.|.:|..:|..||     ||.:                     ::.||.| |...
Human   405 NRRASQMLLMFLLAICLLAIIFVPQEMQTLRE---------------------VLATLGL-GASA 447

  Fly   492 ITSSFAVIYTFTAEMMPTVIRSGGVGVMSTFARFGAMLAPFVPLLASYYDPLPLLLFGTLSLVAG 556
            :.::.|  :....|::||:||:..:|:.:|||.....|||.:.:|:.|..|||.:::|....::|
Human   448 LANTLA--FAHGNEVIPTIIRARAMGINATFANIAGALAPLMMILSVYSPPLPWIIYGVFPFISG 510

  Fly   557 LLSLLLPETFNRKLPDTVEE 576
            ...||||||.|:.|.||:::
Human   511 FAFLLLPETRNKPLFDTIQD 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4630	NP_001260948.1	2A0119	23..573	CDD:273328	162/592 (27%)
		MFS	158..533	CDD:119392	105/404 (26%)
SLC22A9	NP_543142.2	Sugar_tr	11..527	CDD:331684	162/592 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	528..553		0/3 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153763
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.940