Protein Alignment CG4630 and sv2b

DIOPT Version :9

• Sequence 1: NP_001260948.1
• Gene: CG4630 / 36458
• FlyBaseID: FBgn0033809
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: XP_002933355.1
• Gene: sv2b / 100497731
• XenbaseID: XB-GENE-6041859
• Length: 711
• Species: Xenopus tropicalis
• Alignment Length: 697
• Identity: 126/697 - (18%)
• Similarity: 216/697 - (30%)
• Gaps: 259/697 - (37%)

  Fly    65 ECDKLVDAEYGANWVSIAVPGSWSKRGHFTPSTCERFVANGDHLESSSDPWSAWPLDQCFAENFT 129
            |.|::.:.||.      .:|.....|.|...|..:.|          .||      ....||...
 Frog    72 EDDEIYEGEYQ------GIPHPDDLRQHKASSIRDEF----------KDP------ADIIAERIE 114

  Fly   130 TETERCNQFVYGSSERTIVQ-------QWGLQCPENLWKLA------------------------ 163
            .|.:...|:      ..|:|       ||.|.....|..:|
 Frog   115 DEEQLAYQY------ENIIQECGHGRFQWTLFVVLGLALMADGVEVFVVGFVLPSAEKDMCLSRS 173

  Fly   164 ---FVGTIHFAGLVVGTALSGYLADRYGRKHIFLFCIVFMALTGVAQALSWDYISFLFFALLNAV 225
               .:|.|.:.|:::|..:.|.|||:.|||...:..:...|......:....|..|||..|::..
 Frog   174 NKGMLGLIVYLGMMLGAFVWGGLADKVGRKKCLIISLTINAAFSFVSSFVQGYGLFLFCRLISGF 238

  Fly   226 GTSGVYPLAFIIGVEMVGPRKREMSSIVLNYFYAVGEAL-----------------LGLSVFLPD 273
            |..|..|:.|....|.:...||......|..|:.:|...                 :|.......
 Frog   239 GIGGSLPIVFAYFSEFLAREKRGEHLSWLCMFWMIGAVYAAAMAWSIIPHYGWGFSMGTHYHFHS 303

  Fly   274 WRQLQLALSVPPLICVAYFWLVPESVRWLLARNRREQAGVIIRRAAKVNRRD-------ISVELM 331
            ||...:...:|.:..:.....:|||.|:||...:.::|.:|::.....|.|.       .:|..:
 Frog   304 WRVFVVICVLPCIASIIALKFMPESPRFLLETGKHDEAWMILKNIHDTNMRAKGEPEKVFTVSHI 368

  Fly   332 ASFKQQ----ELDAETG---QEDDVEGGLHVKKDDKIWLAVKEVARS--HILMGRY----AILLL 383
            .:.||.    |:.:.||   |...|          :|...:|::..:  |...|::    ..|.:
 Frog   369 KTPKQPDEFIEIQSSTGTWFQRWFV----------RIMTVIKQIWENMLHCFSGQFRKNTIFLAV 423

  Fly   384 IWAVNAIVYYGLSL------------------------NATSLSGN------------------- 405
            :|...::.||||::                        |..:.:.|
 Frog   424 VWFTMSLSYYGLTVWFPDTIRYLQDEDYASKVKRFTDENVKNFNFNFTLENQIHEDGEYYNDRFY 488

  Fly   406 ----KYLNFA------------------------------------------------------- 411
                ||:.|.
 Frog   489 KMKLKYVTFKDSLFDECYFEDVTSTGSIFENCTIQNTVFYNTDLYQHKFIDCNFINVTFSQPKEG 553

  Fly   412 -----------LVCLVE-------IPGYSLAWLFLRRFGRRVALSGSLLLCSITCVASGFVTLAQ 458
                       |:.||.       :||..::.|.:.:.||...::||:|:.::.|.   |:....
 Frog   554 CHIDFEEDNDFLIYLVSFLGSLSVLPGNIISALLMDKIGRIRMIAGSMLISAVCCF---FLFFGN 615

  Fly   459 GDWIPCQTGVESRHSWSCANWLVVTLFLVGKLGITSSFAVIYTFTAEMMPTVIRSGGVGVMSTFA 523
            .:        .:...|.|       ||....:...::..|:   |.|:.||..|:...|:::...
 Frog   616 SE--------SAMIGWQC-------LFCGTSIAAWNALDVV---TVELYPTNKRATAFGILNGLC 662

  Fly   524 RFGA-----MLAPFVPLLASYYDPLPLLLFGTLSLVAGLLSLLLPET 565
            :..|     :.|.||.:.    ..:|:||..|..:..||:||.||||
 Frog   663 KLAAIFGNSIFASFVGIT----KVIPILLASTALVGGGLISLRLPET 705

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4630	NP_001260948.1	2A0119	23..573	CDD:273328	126/697 (18%)
		MFS	158..533	CDD:119392	92/563 (16%)
sv2b	XP_002933355.1	synapt_SV2	1..711	CDD:130366	126/697 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910