DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4630 and slc22a13

DIOPT Version :9

Sequence 1:	NP_001260948.1	Gene:	CG4630 / 36458	FlyBaseID:	FBgn0033809	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	XP_031760340.1	Gene:	slc22a13 / 100491580	XenbaseID:	XB-GENE-959647	Length:	547	Species:	Xenopus tropicalis

Alignment Length:	570	Identity:	162/570 - (28%)
Similarity:	278/570 - (48%)	Gaps:	67/570 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 DFDDILVEIGEFGRFQRRNYLLICLPVLFAAANSLSYVFTAGSPTYRCYVPECDKLVDAEYGANW 78
            ||.:||..:|||||||::..:::.|.....|.:..|.||......:||             .:.|
Frog     3 DFAEILKNVGEFGRFQKQLVVVLSLLSFLNAFHMFSQVFMEIPVPHRC-------------DSRW 54

  Fly    79 VSIAVPG-SWSKRGHFTPSTCERFVANGDH---LESSSDPWSAWPLDQCFAENFTTETERCNQFV 139
            :.:..|. :.::|.::|.....|    |.:   |..|...|....::: |..|.|...:  :.:.
Frog    55 ILLINPNLTEAERLNYTIPRDGR----GQYEQCLMYSPVQWDMESIEK-FGLNSTGPCQ--DGWE 112

  Fly   140 YGSSER--TIVQQWGLQCPENLWKLAFVGTIHFAGLVVGTALSGYLADRYGRKHIFLFCIVFMAL 202
            |.:||:  |:|.|:.|.| ....:.....:::.:||::|..|.|.|.||.||:.:.|..::...:
Frog   113 YDTSEQKSTLVTQFDLVC-HRREQTGISQSVYMSGLLIGALLFGPLGDRIGRRPVILLSMLLQLV 176

  Fly   203 TGVAQALSWDYISFLFFALLNAVGTSGVYPLAFIIGVEMVGPRKREMSSIVLNYFYAVG-EALLG 266
            .|::.|.:..:..:..|..:.....||:.....::|.|.||..:|..::|..:..:||| .||.|
Frog   177 FGLSAAFAPHFYVYTAFRWVVGTSMSGLMINNLVLGAEWVGSSRRACATITAHVCFAVGLMALAG 241

  Fly   267 LSVFLPDWRQLQLALSVPPLICVAYFWLVPESVRWLLARNRREQAGVIIRRAAKVNRRDISVELM 331
            :|..:.:||.||:..|.|..:...|.|::|||.||||.:.::|:|..::::||.:|:::|..:|:
Frog   242 VSYGIRNWRLLQIVSSAPTALLFFYIWVLPESARWLLTKGKKEKAVKLLKKAAAMNKKEIPEDLL 306

  Fly   332 ASFKQQELDAETGQEDDVEGGLHVKKDDKIWLAVKEVARSHILMGRYAILLLIWAVNAIVYYGLS 396
            ..| .:|...::|...|                   :.|:..|.....::.|:|.||::||||||
Frog   307 FQF-NEEKSPKSGNMID-------------------LFRNKTLRKLTLVMCLVWFVNSLVYYGLS 351

  Fly   397 LNATSLSGNKYLNFALVCLVEIPGYSLAWLFLRRFGRRVALSGSLLLCSITCVASGFVTLAQGDW 461
            ||..|...:.||...:...||||....|...::.|||:.:....|.|....|:   .:|.
Frog   352 LNVGSFGLDIYLTQLVFGAVEIPARIGAMFAVQLFGRKPSQMFCLFLGGTVCL---IITA----- 408

  Fly   462 IPCQTGVESRHSWSCANWLVVTLFLVGKLGITSSFAVIYTFTAEMMPTVIRSGGVGVMSTFARFG 526
            ||....:           .:..|.::||..|.|||::.|.:.||:.|||||..|||:.|..||..
Frog   409 IPRNLPI-----------AITILAVIGKFSIASSFSICYIYAAEVFPTVIRQNGVGLASMAARVA 462

  Fly   527 AMLAPFVPLLASYYDPLPLLLFGTLSLVAGLLSLLLPETFNRKLPDTVEE 576
            .:.||.:.||..|:..:|:.::|:..::.|:|..|||||.|:.|.|..::
Frog   463 GITAPLISLLDKYHAAIPMAIYGSGPIIGGILCFLLPETRNKDLQDHTQQ 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4630	NP_001260948.1	2A0119	23..573	CDD:273328	157/556 (28%)
CG4630	NP_001260948.1	MFS	158..533	CDD:119392	109/375 (29%)
slc22a13	XP_031760340.1	2A0119	12..509	CDD:273328	157/556 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020