DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4630 and slc22a20p.1

DIOPT Version :9

Sequence 1:	NP_001260948.1	Gene:	CG4630 / 36458	FlyBaseID:	FBgn0033809	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	XP_004913725.1	Gene:	slc22a20p.1 / 100489586	XenbaseID:	XB-GENE-6463910	Length:	572	Species:	Xenopus tropicalis

Alignment Length:	595	Identity:	164/595 - (27%)
Similarity:	276/595 - (46%)	Gaps:	103/595 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LDFDDILVEIGEFGRFQRRNYLLICLPVLFAAANSLSYVFTAGSPTYRCYVPECDKLVDAEYGAN 77
            :.|:|:|:.:|..||||..:..::.:|:||...::....|:|..|.:||:||..|... ..|..:
Frog     1 MGFNDLLLSVGGLGRFQIIHTTMLLIPMLFMGCHNFLQNFSAAVPAHRCWVPSLDNNT-MGYDQD 64

  Fly    78 WVSIAVPGSWSKRGHFTPSTCERF-------VANG---DHLESSSDPWSAWPLDQCFAENFTTET 132
            .:...:|...|::    |.:|.|:       ..||   :|.|...|.|
Frog    65 HLPAFIPMDESEK----PLSCLRYRKALHSMWTNGTSTNHTEPCEDGW----------------- 108

  Fly   133 ERCNQFVYGSSE--RTIVQQWGLQCPENLWKLAFVG-TIHFAGLVVGTALSGYLADRYGRKHIFL 194
                  ||..|:  .|||.:|.|.|  .|.|:..:. :|:.||::||..|.|.|:||.||:.:.:
Frog   109 ------VYDKSDFSSTIVTEWDLVC--KLRKMRQIAQSIYMAGVLVGAVLLGGLSDRLGRRALLI 165

  Fly   195 FCIVFMALTGVAQALSWDYISFLFFALLNAVGTSGVYPLAFIIGVEMVGPRKREMSSIVLNYFYA 259
            ...:.||:.|...|...::|::..|..|..:..||:......:.:|...|:.|.:...:....:.
Frog   166 GSNLVMAVCGTCAAFLPNFITYCTFRCLCGIAFSGITLNTNSLILEWTPPKGRTIMGTLFAAGFT 230

  Fly   260 VGEALL-GLSVFLPDWRQLQLALSVPPLICVAYFWLVPESVRWLLARNRREQAGVIIRRAAKVN- 322
            .|:.|| .|:..:.:||.||.|:|.|......|.||||||.|||:.:.|..:|...::|.|.:|
Frog   231 CGQILLAALAYGIREWRWLQFAVSAPFYFFFLYSWLVPESARWLILKGRSHEALKALQRVAIING 295

  Fly   323 RRD----ISVELMASFKQQELDAETGQEDDVEGGLHVKKDDKIWLAVKEVARSHIL--------M 375
            :|:    :|..::.|..|.||:                          :|.|.|.|        |
Frog   296 KREEGQKLSEMILISHMQSELN--------------------------QVKRPHSLFDLFRTPGM 334

  Fly   376 GRYAI-LLLIWAVNAIVYYGLSLNATSLSGNKYLNFALVCLVEIPGYSLAWLFLRRFGRRVALSG 439
            .:..| |:::|..:.:.:|||.::..:...:.:|.......:::|...:|.|.:...||||..:.
Frog   335 RKVTICLMMVWFSSGVAFYGLGMDLQNFGISIFLLQFTFGAIDMPAKVVAALLMTYMGRRVTQAT 399

  Fly   440 SLLLCSITCVASGFVTLAQGDWIPCQTGVESRHSWSCANWLVVTLFLVGKLGITSSFAVIYTFTA 504
            .|:|..:..:.:.|:  .||..|                 |.:.|.:.||..:.:|||..|.|:.
Frog   400 VLILSGVALLTNAFI--PQGMKI-----------------LRMVLAVFGKGCMAASFACAYLFSG 445

  Fly   505 EMMPTVIRSGGVGVMSTFARFGAMLAPFVPLLASYYDPLPLLLFGTLSLVAGLLSLLLPETFNRK 569
            |:.|||||..|:||::..||.|:::||.|.||......||..::|..:::||..:..|.||.|::
Frog   446 ELFPTVIRQTGMGVVAMMARVGSVVAPLVLLLWEISPILPSAIYGIAAIIAGGAATFLMETNNQQ 510

  Fly   570 LPDTVEEAIA 579
            ||::|||..|
Frog   511 LPESVEEVEA 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4630	NP_001260948.1	2A0119	23..573	CDD:273328	157/577 (27%)
CG4630	NP_001260948.1	MFS	158..533	CDD:119392	106/390 (27%)
slc22a20p.1	XP_004913725.1	MFS	101..485	CDD:391944	121/453 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010